0000000000393889
AUTHOR
Chandrajit P. Raut
showing 2 related works from this author
Individualisierte Chirurgie bei Magen-GIST
2013
Im Gegensatz zu den Magenkarzinomen eignen sich GIST (gastrointestinale Stromatumoren) deutlich besser fur einen laparoskopischen Ansatz. Geringer Sicherheitsabstand (1–2 cm), fehlende Indikation zur Lymphadenektomie, gute Ansprache auf eine Chemotherapie mit Tyrosinkinasehemmern – all diese Faktoren begunstigen die Moglichkeiten des laparoskopischen Zugangs.
Guidelines for time-to-event end point definitions in sarcomas and gastrointestinal stromal tumors (GIST) trials: results of the DATECAN initiative (…
2015
ABSTRACT The DATECAN initiative (Definition for the Assessment of Time-to-event Endpoints in CANcer trials) aims to provide recommendations for definitions of time-to-event end points in cancer randomized controlled trials. We relied on a consensus method based on a multidisciplinary panel of experts to develop these guidelines for trials on sarcomas and gastrointestinal stromal tumors. Background The use of potential surrogate end points for overall survival, such as disease-free survival (DFS) or time-to-treatment failure (TTF) is increasingly common in randomized controlled trials (RCTs) in cancer. However, the definition of time-to-event (TTE) end points is rarely precise and lacks unif…