0000000000395374

AUTHOR

James Ronald

showing 2 related works from this author

Local Tumor Control and Patient Outcome Using Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma: iRECIST as a Potential Substitute for…

2019

Objective. The purpose of this study was to investigate whether, compared with traditional criteria, the modified Response Evaluation Criteria in Solid Tumors version 1.1 for immune-based therapeutics (iRECIST) improves prediction of local tumor control and survival in patients with hepatocellular carcinoma (HCC) treated with stereotactic body radiotherapy (SBRT). Materials and Methods. Fifty-one HCC lesions (mean size, 3.1 cm) treated with SBRT in 41 patients (mean age, 67 years) were retrospectively included. Each patient underwent CT or MRI before SBRT and at least once after SBRT. Best overall response was categorized using Response Evaluation Criteria in Solid Tumors version 1.1 (RECIS…

Malemedicine.medical_specialtyCarcinoma HepatocellularHepatocellular carcinomamedicine.medical_treatmentContrast MediaRadiosurgeryRadiosurgerySurvival analysiMcNemar's testRetrospective StudieResponse Evaluation Criteria in Solid Tumors (RECIST)Local recurrenceTargeted radiotherapymedicineHumansRadiology Nuclear Medicine and imagingSurvival rateResponse Evaluation Criteria in Solid TumorsSurvival analysisRetrospective StudiesAgedAged 80 and overbusiness.industryLiver NeoplasmsGeneral MedicineMiddle Agedmedicine.diseaseSurvival RateExact testTreatment OutcomeLiver NeoplasmResponse Evaluation Criteria in Solid TumorsHepatocellular carcinomaFemaleRadiologybusinessProgressive diseaseHumanAmerican Journal of Roentgenology
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Reproducibility of CT Radiomic Features within the Same Patient: Influence of Radiation Dose and CT Reconstruction Settings.

2019

Background Results of recent phantom studies show that variation in CT acquisition parameters and reconstruction techniques may make radiomic features largely nonreproduceable and of limited use for prognostic clinical studies. Purpose To investigate the effect of CT radiation dose and reconstruction settings on the reproducibility of radiomic features, as well as to identify correction factors for mitigating these sources of variability. Materials and Methods This was a secondary analysis of a prospective study of metastatic liver lesions in patients who underwent staging with single-energy dual-source contrast material-enhanced staging CT between September 2011 and April 2012. Technique p…

MaleContrast MediaRadiation Dosage030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineMedicineHumansRadiology Nuclear Medicine and imagingProspective StudiesCluster analysisNeoplasm StagingReproducibilitybusiness.industryRadiation doseLiver NeoplasmsReproducibility of ResultsReconstruction algorithmMiddle AgedHierarchical clusteringFeature (computer vision)radiomics030220 oncology & carcinogenesisRadiographic Image Interpretation Computer-AssistedFemaleTomographybusinessNuclear medicineTomography X-Ray ComputedCt reconstructionAlgorithmsRadiology
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