Abstract of the 68th Meeting (Spring Meeting) 6–9 March 1990, Heidelberg

Funktionen des Magen-Darm-Kanals

Hauptaufgabe des Gastrointestinaltrakts ist es, die aufgenommene Nahrung in resorbierbare Bestandteile umzuwandeln und diese in den Korper aufzunehmen. Diese Vorgange werden durch mechanische Prozesse (Zerkleinerung, Durchmischung, Transport) und die Sekretion von Verdauungssaften mit ihren Enzymen eingeleitet. Durch diese Enzyme werden Eiweise, Fette und Kohlenhydrate hydrolytisch gespalten und in resorbierbare Bruchstucke zerlegt (Verdauung). Die Endprodukte der Verdauung sowie Wasser, Mineralstoffe und Vitamine werden aus dem Darmlumen durch die Darmschleimhaut hindurch in das Blut und die Lymphe aufgenommen (Resorption).

Bacteremia after proctoscopy and hemorrhoidal injection sclerotherapy

The incidence of bacteremia following proctoscopy and hemorrhoidal injection sclerotherapy was studied in 50 outpatients undergoing both procedures. Bacteremia was found in 2 per cent of the subjects after proctoscopy and in 8 per cent after sclerotherapy. None of the subjects developed symptoms of septicemia following the procedure. It is concluded that antibiotic prophylaxis should be used before sclerotherapy in patients with valvular heart disease or compromised host defense.

Antiinflammatory treatment and intestinal alpha 1-antitrypsin clearance in active Crohn's disease.

Intestinal alpha 1-antitrypsin clearance was quantified in 17 patients with clinically active Crohn's disease before and after a six-week period of treatment with sulfasalazine and methylprednisolone. Before the study, alpha 1-antitrypsin clearance and, hence, enteric protein loss was elevated as being above control values in 16 patients. After therapy, clearance values decreased in 11 and were normalized in five patients. Serum albumin level was normalized in 11 of 12 patients who had hypoalbuminemia before the study. Clinical condition was improved in all but 1 patient after treatment. There was no close correlation between alpha 1-antitrypsin clearance and disease activity index. These r…

Influence of Rhein on Rat Colonic Na<sup>+</sup>, K<sup>+</sup>-ATPase and Permeability in vitro

Rhein, an aglucone of a laxative-acting anthraquinone, which induces net secretion in the human jejunum and colon, does not induce net secretion under open circuit current in in vitro conditions but r