0000000000400752

AUTHOR

Nils Haller

0000-0002-7066-7615

showing 2 related works from this author

Platelets, endothelial cells and leukocytes contribute to the exercise-triggered release of extracellular vesicles into the circulation.

2019

ABSTRACT Physical activity initiates a wide range of multi-systemic adaptations that promote mental and physical health. Recent work demonstrated that exercise triggers the release of extracellular vesicles (EVs) into the circulation, possibly contributing to exercise-associated adaptive systemic signalling. Circulating EVs comprise a heterogeneous collection of different EV-subclasses released from various cell types. So far, a comprehensive picture of the parental and target cell types, EV-subpopulation diversity and functional properties of EVs released during exercise (ExerVs) is lacking. Here, we performed a detailed EV-phenotyping analysis to explore the cellular origin and potential …

0301 basic medicineimmunobead isolationCell typeHistologyCD14exosomes03 medical and health sciences0302 clinical medicinePlateletlcsh:QH573-671Antigen-presenting cellplasmaCluster of differentiationCD63exerciselcsh:CytologyChemistrysize exclusion chromatographyCell BiologyExtracellular vesiclesmultiplex phenotypingMicrovesiclesCell biology030104 developmental biology030220 oncology & carcinogenesisCD146extracellular vesiclesResearch Article
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Twelve-Week Internet-Based Individualized Exercise Program in Adults With Systemic Lupus Erythematosus: Protocol for a Randomized Controlled Trial

2020

Background Systemic lupus erythematosus is a systemic autoimmune disease, which is associated with high cardiovascular risk, a predisposition to metabolic disorders, muscle wasting, and fatigue. Exercise therapy has become an important part of the long-term treatment of comorbidities in systemic lupus erythematosus. Exercise can lead to various benefits in patients with systemic lupus erythematosus such as increased aerobic capacity and exercise tolerance, resulting in an increased quality of life, decreased depression, and decreased fatigue. At the moment, no evidence-based treatment guidelines that recommend exercise for patients with systemic lupus erythematosus exist. Also, the efficac…

medicine.medical_specialtyPhysical fitnessComputer applications to medicine. Medical informaticsR858-859.7physical activitylaw.invention03 medical and health sciences0302 clinical medicinesystemic lupus erythematosusQuality of lifeRandomized controlled triallawinternet-based exercise program disease activityInternal medicineProtocolmedicineAerobic exerciseOutpatient clinic030212 general & internal medicineWasting030203 arthritis & rheumatologybusiness.industryRGeneral MedicineRheumatologyMedicinefatiguemedicine.symptombusinessAnaerobic exerciseJMIR Research Protocols
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