0000000000400993

AUTHOR

Pegah Khosravi

showing 2 related works from this author

Deep learning enables robust assessment and selection of human blastocysts after in vitro fertilization

2019

AbstractVisual morphology assessment is routinely used for evaluating of embryo quality and selecting human blastocysts for transfer after in vitro fertilization (IVF). However, the assessment produces different results between embryologists and as a result, the success rate of IVF remains low. To overcome uncertainties in embryo quality, multiple embryos are often implanted resulting in undesired multiple pregnancies and complications. Unlike in other imaging fields, human embryology and IVF have not yet leveraged artificial intelligence (AI) for unbiased, automated embryo assessment. We postulated that an AI approach trained on thousands of embryos can reliably predict embryo quality with…

animal structuresmedicine.medical_treatmentmedia_common.quotation_subjectDecision treeMedicine (miscellaneous)Health InformaticsFertilityBiologyMachine learningcomputer.software_genrelcsh:Computer applications to medicine. Medical informaticsArticle03 medical and health sciences0302 clinical medicineHealth Information ManagementImage processingMachine learningmedicineBlastocyst030304 developmental biologymedia_common0303 health sciencesPregnancy030219 obstetrics & reproductive medicineIn vitro fertilisationbusiness.industryDeep learningEmbryomedicine.disease3. Good healthComputer Science Applicationsmedicine.anatomical_structureembryonic structureslcsh:R858-859.7Artificial intelligencebusinesscomputerEmbryo qualityNPJ Digital Medicine
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Robust Automated Assessment of Human Blastocyst Quality using Deep Learning

2018

AbstractMorphology assessment has become the standard method for evaluation of embryo quality and selecting human blastocysts for transfer inin vitro fertilization(IVF). This process is highly subjective for some embryos and thus prone to human bias. As a result, morphological assessment results may vary extensively between embryologists and in some cases may fail to accurately predict embryo implantation and live birth potential. Here we postulated that an artificial intelligence (AI) approach trained on thousands of embryos can reliably predict embryo quality without human intervention.To test this hypothesis, we implemented an AI approach based on deep neural networks (DNNs). Our approac…

animal structuresComputer sciencemedia_common.quotation_subjectmedicine.medical_treatmentMachine learningcomputer.software_genre03 medical and health sciences0302 clinical medicinemedicineQuality (business)Blastocyst030304 developmental biologymedia_common0303 health sciencesPregnancy030219 obstetrics & reproductive medicineIn vitro fertilisationbusiness.industryDeep learningEmbryomedicine.diseasemedicine.anatomical_structureembryonic structuresArtificial intelligencebusinessLive birthcomputerEmbryo quality
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