0000000000402117

AUTHOR

R. Mcdonnell

showing 3 related works from this author

Anorectal malformations and pregnancy-related disorders: a registry-based case-control study in 17 European regions

2013

Objective To identify pregnancy-related risk factors for different manifestations of congenital anorectal malformations (ARMs).Design A population-based case-control study.Setting Seventeen EUROCAT (European Surveillance of Congenital Anomalies) registries, 1980-2008.Population The study population consisted of 1417 cases with ARM, including 648 cases of isolated ARM, 601 cases of ARM with additional congenital anomalies, and 168 cases of ARM-VACTERL (vertebral, anal, cardiac, tracheo-esophageal, renal, and limb defects), along with 13371 controls with recognised syndromes or chromosomal abnormalities.Methods Multiple logistic regression analyses were used to calculate adjusted odds ratios …

ANOMALIESaetiologyMaternalLogistic regressionAnus ImperforateEpilepsyPre-EclampsiaMEDICATION USEPregnancyRisk FactorsOdds RatioAetiologymedia_commoneducation.field_of_studyObstetricsMATERNAL EXPOSUREObstetrics and GynecologyAnal atresiaCONGENITAL-MALFORMATIONSAnorectal MalformationsEuropeParityHuman Reproduction Renal disorder [NCEBP 12]Population studyFemaleAnal Atresiamedicine.medical_specialtyFeverReproductive Techniques Assistedmedia_common.quotation_subjectPopulationFertilityGenomic disorders and inherited multi-system disorders [IGMD 3]VACTERLmedicineanorectal malformations; anal atresia; birth defects; aetiology; maternal; pregnancy; VACTERLHumansAbnormalities MultipleBirth DefectseducationPregnancyEpilepsybusiness.industryRENACCase-control studyInfant NewbornAbortion InducedOdds ratioBIRTH-DEFECTS PREVENTIONBECKWITH-WIEDEMANN-SYNDROMEHuman Reproducion Genomic disorders and inherited multi-system disorders [NCEBP 12]Estados de Saúde e de Doençamedicine.diseasePregnancy Complicationsmaternalbirth defectsEvaluation of complex medical interventions [NCEBP 2]Case-Control StudiesRISK-FACTORSPregnancy TwinMULTIPLE BIRTHSbusinessIN-VITRO FERTILIZATION
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Prevalence of microcephaly in Europe: population based study.

2016

Objectives: Microcephaly is a congenital anomaly where the baby’s head is smaller than expected when compared with babies of the same sex, age and ethnicity. Many of these babies will have underdeveloped brains. This study aimed to provide contemporary estimates of the prevalence of microcephaly in Europe, determine if the diagnosis of microcephaly is consistent across Europe and to evaluate whether changes in prevalence would be detected using the current European surveillance performed by EUROCAT (the European Surveillance of Congenital Anomalies). Design: A questionnaire and a population-based, observational study Setting: 24 EUROCAT registries covering 570,000 births annually in 15 coun…

MalePediatricsmedicine.medical_specialtyMicrocephalyPrenatal diagnosisEthnic originmicrocephaly ; prevalence surveillance03 medical and health sciencessymbols.namesakeEuropean Surveillance of Congenital Anomalies0302 clinical medicineMicrocefaliaEuropean SurveillancePregnancyEUROCAT030225 pediatricsStatistical significancePrenatal DiagnosisSurveys and QuestionnairesmedicinePrevalenceJournal ArticleHumans030212 general & internal medicinePoisson regressionRegistriesEurope/epidemiology; Female; Fetal Death; Humans; Male; Microcephaly/diagnosis; Microcephaly/epidemiology; Population Surveillance; Pregnancy; Prenatal Diagnosis; Prevalence; Registries; Retrospective Studies; Surveys and QuestionnairesFetal DeathRetrospective StudiesPregnancyZIKA VIRUS-INFECTIONbusiness.industryResearchRENACRetrospective cohort studyGeneral Medicinemedicine.diseaseEstados de Saúde e de DoençaObservação em Saúde e VigilânciaCongenital AnomaliesConfidence intervalEuropeCONGENITAL-ANOMALIESPopulation SurveillancesymbolsMicrocephalyFemalebusiness
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Trends in congenital anomalies in Europe from 1980 to 2012

2018

Background Surveillance of congenital anomalies is important to identify potential teratogens. Methods This study analysed the prevalence of 61 congenital anomaly subgroups (excluding chromosomal) in 25 population-based EUROCAT registries (1980–2012). Live births, fetal deaths and terminations of pregnancy for fetal anomaly were analysed with multilevel random-effects Poisson regression models. Results Seventeen anomaly subgroups had statistically significant trends from 2003±2012; 12 increasing and 5 decreasing. Conclusions The annual increasing prevalence of severe congenital heart defects, single ventricle, atrioventricular septal defects and tetralogy of Fallot of 1.4% (95% CI: 0.7% to …

MaleMaternal HealthLimb Reduction Defectslcsh:MedicineHEART-DEFECTS030204 cardiovascular system & hematologyFOLIC-ACID FORTIFICATIONPathology and Laboratory MedicineGeographical Locations0302 clinical medicineEUROCATPregnancyDuctus arteriosusPrevalenceMedicine and Health SciencesMorphogenesis030212 general & internal medicineRegistrieslcsh:ScienceTetralogy of FallotRISKStenosiseducation.field_of_studyMultidisciplinaryObstetricsIncidence (epidemiology)Obstetrics and GynecologyHeartASSOCIATIONCongenital Heart DefectsCongenital AnomaliesEuropePOPULATION-BASED EVALUATIONmedicine.anatomical_structurecongenital anomalies ; surveillance epidemiologyPopulation SurveillanceMicrocephalyNEURAL-TUBE DEFECTSFemaleAnatomyResearch Articlemedicine.medical_specialtyCardiac VentriclesPopulationCardiologyHistory 21st CenturyDuodenal atresiaEurope/epidemiologyCongenital Abnormalities03 medical and health sciencesSigns and SymptomsDiagnostic MedicinemedicineCongenital DisordersHumansBirth DefectseducationPregnancyZIKA VIRUS-INFECTIONbusiness.industrylcsh:RBiology and Life SciencesHistory 20th Centurymedicine.diseaseCongenital Abnormalities/diagnosisCongenital Abnormalities/diagnosis; Congenital Abnormalities/epidemiology; Congenital Abnormalities/etiology; Congenital Abnormalities/history; Europe/epidemiology; Female; History 20th Century; History 21st Century; Humans; Male; Population Surveillance; Pregnancy; Prevalence; RegistriesTeratologyREDUCTIONAtresiaPeople and PlacesBirthCardiovascular AnatomyVentricular Septal DefectsWomen's Healthlcsh:QbusinessDevelopmental BiologyPLoS One
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