0000000000402119

AUTHOR

Nathalie Lelong

showing 3 related works from this author

Anorectal malformations and pregnancy-related disorders: a registry-based case-control study in 17 European regions

2013

Objective To identify pregnancy-related risk factors for different manifestations of congenital anorectal malformations (ARMs).Design A population-based case-control study.Setting Seventeen EUROCAT (European Surveillance of Congenital Anomalies) registries, 1980-2008.Population The study population consisted of 1417 cases with ARM, including 648 cases of isolated ARM, 601 cases of ARM with additional congenital anomalies, and 168 cases of ARM-VACTERL (vertebral, anal, cardiac, tracheo-esophageal, renal, and limb defects), along with 13371 controls with recognised syndromes or chromosomal abnormalities.Methods Multiple logistic regression analyses were used to calculate adjusted odds ratios …

ANOMALIESaetiologyMaternalLogistic regressionAnus ImperforateEpilepsyPre-EclampsiaMEDICATION USEPregnancyRisk FactorsOdds RatioAetiologymedia_commoneducation.field_of_studyObstetricsMATERNAL EXPOSUREObstetrics and GynecologyAnal atresiaCONGENITAL-MALFORMATIONSAnorectal MalformationsEuropeParityHuman Reproduction Renal disorder [NCEBP 12]Population studyFemaleAnal Atresiamedicine.medical_specialtyFeverReproductive Techniques Assistedmedia_common.quotation_subjectPopulationFertilityGenomic disorders and inherited multi-system disorders [IGMD 3]VACTERLmedicineanorectal malformations; anal atresia; birth defects; aetiology; maternal; pregnancy; VACTERLHumansAbnormalities MultipleBirth DefectseducationPregnancyEpilepsybusiness.industryRENACCase-control studyInfant NewbornAbortion InducedOdds ratioBIRTH-DEFECTS PREVENTIONBECKWITH-WIEDEMANN-SYNDROMEHuman Reproducion Genomic disorders and inherited multi-system disorders [NCEBP 12]Estados de Saúde e de Doençamedicine.diseasePregnancy Complicationsmaternalbirth defectsEvaluation of complex medical interventions [NCEBP 2]Case-Control StudiesRISK-FACTORSPregnancy TwinMULTIPLE BIRTHSbusinessIN-VITRO FERTILIZATION
researchProduct

Prenatal diagnosis and epidemiology of multicystic kidney dysplasia in Europe

2014

ObjectivesThe aim of this study is to describe the prenatal diagnosis and epidemiology of multicystic kidney dysplasia (MCKD). MethodsThe study is based on routinely collected data from a European database of major congenital anomalies including 13 registries with cases born in 1997-2006 and covering 1458552 births. ResultsThere were 601 MCKD cases giving an overall prevalence of 4.12 per 10000 births with regional variation. In live births, 87% of cases had an isolated renal anomaly and 13% had associated major nonrenal anomalies (chromosomal, syndrome or other major anomalies). For the cases with isolated renal anomalies, 51/386 (11%) and 7/386 (2%) choose to terminate the pregnancy or re…

medicine.medical_specialtyPediatricsPregnancyMulticystic Kidney DysplasiaFetal deathbusiness.industryObstetrics and GynecologyPrenatal diagnosismedicine.diseaseRenal anomalyEpidemiologyMedicineDetection ratebusinessGenetics (clinical)Prenatal Diagnosis
researchProduct

Use of asthma medication during pregnancy and risk of specific congenital anomalies: A European case-malformed control study.

2015

Background: Pregnant women with asthma need to take medication during pregnancy.Objective: We sought to identify whether there is an increased risk of specific congenital anomalies after exposure to antiasthma medication in the first trimester of pregnancy.Methods: We performed a population-based case-malformed control study testing signals identified in a literature review. Odds ratios (ORs) of exposure to the main groups of asthma medication were calculated for each of the 10 signal anomalies compared with registrations with nonchromosomal, nonsignal anomalies as control registrations. In addition, exploratory analyses were done for each nonsignal anomaly. The data set included 76,249 reg…

PediatricsINFANTSAdrenal Cortex HormonesPregnancyOdds RatioImmunology and AllergyAnti-Asthmatic AgentsPOPULATIONAsthma medicationTetralogy of FallotMATERNAL ASTHMAeducation.field_of_studyOUTCOMESWOMEN3. Good healthPREVALENCEEuropeAnesthesiaPrenatal Exposure Delayed Effectsinhaled β2-agonistsFemalemedicine.drugRiskmedicine.medical_specialty1ST TRIMESTERfirst trimester exposurePopulationImmunologyUNITED-STATESCongenital AbnormalitiesAsthma medication ; congenital anomalies ; first trimester exposure ; inhaled corticosteroids ; inhaled β(2)-agonists ; pregnancy.:Medisinske Fag: 700 [VDP]medicineHumansMALFORMATIONSeducationAdrenergic beta-2 Receptor AgonistsMETAANALYSISAsthmaPregnancySpina bifidaGastroschisisbusiness.industrycongenital anomaliesOdds ratiomedicine.diseaseAsthmainhaled beta(2)-agonistsPregnancy Trimester FirstCase-Control StudiesSalbutamolinhaled corticosteroidsbusinessThe Journal of allergy and clinical immunology
researchProduct