0000000000402899

AUTHOR

Sana Ullah

showing 4 related works from this author

Olfactory discrimination ability and brain expression of c-fos, Gir and Glut1 mRNA are altered in n-3 fatty acid-depleted rats

2007

Abstract The long-chain polyunsaturated n  − 3 fatty acids ( n  − 3 PUFA), particularly docosahexaenoic acid (DHA), are abundantly present in the central nervous system and play an important role in cognitive functions such as learning and memory. We, therefore, investigated the effects of n  − 3 PUFA-depletion in rats (F2 generation) on the learning of an olfactory discrimination task, progressively acquired within a four-arm maze, and on the mRNA expression of some candidate genes, i.e., c-fos, Gir and glucose transporter (Glut1), which could reflect the level of cerebral activity. We observed that DHA contents were dramatically decreased in the olfactory bulb, the piriform cortex and the…

MaleTime Factors[SDV]Life Sciences [q-bio]OLFACTORY LEARNINGReceptors G-Protein-CoupledDiscrimination LearningBehavioral Neuroscience0302 clinical medicineDiscrimination PsychologicalPiriform cortexBRAINDiet Fat-Restricted0303 health sciencesGlucose Transporter Type 1NeocortexBehavior AnimalGIRReverse Transcriptase Polymerase Chain ReactionSmellmedicine.anatomical_structureBiochemistryDocosahexaenoic acidN−3 DEFICIENCYOlfactory LearningProto-Oncogene Proteins c-fosmedicine.medical_specialtyN-3 PUFAC-FOSCentral nervous systemOlfactionBiologyAPPRENTISSAGE03 medical and health sciencesInternal medicineFatty Acids Omega-3medicineAnimalsRNA MessengerRats WistarUnsaturated fatty acid030304 developmental biologyAnalysis of VarianceBody WeightDOCOSAHEXAENOIC ACIDOlfactory bulbRatsEndocrinologyGene Expression RegulationRAT030217 neurology & neurosurgeryGLUT1
researchProduct

The global burden of cancer attributable to risk factors, 2010–19 : A systematic analysis for the Global Burden of Disease Study 2019

2022

Background: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods: The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 20…

MaleDEATHSDALY cancer risk factorsMedizinsystematic analysisGlobal HealthRisk AssessmentCancer preventionGlobal Burden of DiseaseRC0254Risk-attributable cancer deathsSDG 3 - Good Health and Well-beingRA0421Risk FactorsRA0421 Public health. Hygiene. Preventive MedicineQuality-Adjusted Life YearNeoplasmscancerHumansGlobal Burden of Disease StudyUKMedicine(all)MCCRC0254 Neoplasms. Tumors. Oncology (including Cancer)Risk FactorSmokingCOVID-193rd-DASGeneral MedicineDisability-adjusted life-yearsSOCIAL DETERMINANTSRisk assessmentsrisk factorCardiovascular and Metabolic Diseases3121 General medicine internal medicine and other clinical medicineOBESITYCancer burden/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingNeoplasmFemaleLIFE-STYLEQuality-Adjusted Life YearsHEALTHRAHumanRC
researchProduct

Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019

2022

Correction to Lancet Public Health 2022; 7: e657-69. Lancet Public Health. 2022 Dec;7(12):e992. doi: 10.1016/S2468-2667(22)00294-8. PMID: 36462522. Background: Globally, transport and unintentional injuries persist as leading preventable causes of mortality and morbidity for adolescents. We sought to report comprehensive trends in injury-related mortality and morbidity for adolescents aged 10-24 years during the past three decades. Methods: Using the Global Burden of Disease, Injuries, and Risk Factors 2019 Study, we analysed mortality and disability-adjusted life-years (DALYs) attributed to transport and unintentional injuries for adolescents in 204 countries. Burden is reported in absolut…

MaleAdolescentRJ101AdolescentsGlobal Burden of DiseaseLife ExpectancyRJ101 Child Health. Child health servicesSDG 3 - Good Health and Well-beingRA0421Risk FactorsRA0421 Public health. Hygiene. Preventive MedicineHumansMortalityChildrenInterventionsMCCUnintentional injuriesPreventionPublic Health Environmental and Occupational Health3rd-DASGBD 2019 Adolescent Transport and Unintentional Injuries Collaborators3142 Public health care science environmental and occupational healthAdolescent transportPreventable causesHealthFemaleQuality-Adjusted Life YearsInvestmentMorbidityAdolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019The Lancet Public Health
researchProduct

Global burden of chronic respiratory diseases and risk factors, 1990-2019: an update from the Global Burden of Disease Study 2019

2023

Background: Updated data on chronic respiratory diseases (CRDs) are vital in their prevention, control, and treatment in the path to achieving the third UN Sustainable Development Goals (SDGs), a one-third reduction in premature mortality from non-communicable diseases by 2030. We provided global, regional, and national estimates of the burden of CRDs and their attributable risks from 1990 to 2019.Methods: Using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we estimated mortality, years lived with disability, years of life lost, disability-adjusted life years (DALYs), prevalence, and incidence of CRDs, i.e. chronic obstructive pulmonary disease (COPD)…

Pulmonary emphysemaLung disease;MorbidityEpidemiologyChronic obstructive pulmonary diseaseInterstitial lung diseaseGeneral MedicinePneumoconiosiAsthmaSDG 3 - Good Health and Well-beingMortality; PneumoconiosisLung diseasePneumoconiosisMorbidityMortality
researchProduct