0000000000403363

AUTHOR

S. Fabiani

showing 5 related works from this author

The Large Observatory for X-ray Timing (LOFT)

2012

High-time-resolution X-ray observations of compact objects provide direct access to strong-field gravity, to the equation of state of ultra-dense matter and to black hole masses and spins. A 10 m^2-class instrument in combination with good spectral resolution is required to exploit the relevant diagnostics and answer two of the fundamental questions of the European Space Agency (ESA) Cosmic Vision Theme "Matter under extreme conditions", namely: does matter orbiting close to the event horizon follow the predictions of general relativity? What is the equation of state of matter in neutron stars? The Large Observatory For X-ray Timing (LOFT), selected by ESA as one of the four Cosmic Vision M…

Event horizonX-ray timingMission7. Clean energy01 natural sciencesneutron starsT175 Industrial research. Research and developmentBINARIESSettore FIS/05 - Astronomia E AstrofisicaALICESILICON DRIFT DETECTORObservatoryEQUATIONneutron star010303 astronomy & astrophysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)Physics[SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]Astrophysics::Instrumentation and Methods for AstrophysicsMissions X-ray timing compact objects black holes neutron starscompact objectsAstrophysics - Instrumentation and Methods for AstrophysicsAstrophysics - High Energy Astrophysical PhenomenaPROPORTIONAL COUNTER[PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]Active galactic nucleusCosmic VisionX-ray astronomy; high time variabilityAstrophysics::High Energy Astrophysical Phenomenablack holes; compact objects; Missions; neutron stars; X-ray timing;FOS: Physical sciencesMissionsX-ray astronomy0103 physical sciencesOSCILLATIONSInstrumentation and Methods for Astrophysics (astro-ph.IM)Supermassive black holehigh time variability010308 nuclear & particles physicsAstronomyCONSTRAINTSAstronomy and Astrophysicsblack holesGalaxyBlack holeNeutron starSpace and Planetary ScienceQB460-466 AstrophysicsDISCOVERYBLACK-HOLESUPERAGILE
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The NHXM observatory

2011

Exploration of the X-ray sky has established X-ray astronomy as a fundamental astrophysical discipline. While our knowledge of the sky below 10 keV has increased dramatically (∼8 orders of magnitude) by use of grazing incidence optics, we still await a similar improvement above 10 keV, where to date only collimated instruments have been used. Also ripe for exploration is the field of X-ray polarimetry, an unused fundamental tool to understand the physics and morphology of X-ray sources. Here we present a novel mission, the New Hard X-ray Mission (NHXM) that brings together for the first time simultaneous high-sensitivity, hard-X-ray imaging, broadband spectroscopy and polarimetry. NHXM will…

Black-holesAcceleration mechanismCosmic Visionmedia_common.quotation_subjectPolarimetry7. Clean energy01 natural sciencesMissionsCosmologyPhysical cosmologyNon-thermal emissionAcceleration mechanism; Accretion physics; Black-holes; Compact objects; Cosmology; Missions; Non-thermal emission; X-ray imaging; X-ray polarimetry; Astronomy and Astrophysics; Space and Planetary ScienceObservatory0103 physical sciencesBroadbandX-ray polarimetry010303 astronomy & astrophysicsCompact objectsmedia_commonPhysics010308 nuclear & particles physicsX-ray imagingVegaAstronomyAstronomy and AstrophysicsAccretion physicsCosmologySkySpace and Planetary ScienceExperimental Astronomy
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XIPE: the x-ray imaging polarimetry explorer

2016

XIPE, the X-ray Imaging Polarimetry Explorer, is a mission dedicated to X-ray Astronomy. At the time of writing XIPE is in a competitive phase A as fourth medium size mission of ESA (M4). It promises to reopen the polarimetry window in high energy Astrophysics after more than 4 decades thanks to a detector that efficiently exploits the photoelectric effect and to X-ray optics with large effective area. XIPE uniqueness is time-spectrally-spatially- resolved X-ray polarimetry as a breakthrough in high energy astrophysics and fundamental physics. Indeed the payload consists of three Gas Pixel Detectors at the focus of three X-ray optics with a total effective area larger than one XMM mirror bu…

X-ray AstronomyHigh-energy astronomyPolarimetryX-ray opticsX-ray telescopeCondensed Matter Physic01 natural sciencesObservatory0103 physical sciencesPolarimetryElectronicOptical and Magnetic MaterialsSpectral resolutionElectrical and Electronic Engineering010303 astronomy & astrophysicsGas Pixel DetectorPhysicsX-ray astronomyta115X-ray optics010308 nuclear & particles physicsElectronic Optical and Magnetic MaterialApplied MathematicsVegaAstronomyComputer Science Applications1707 Computer Vision and Pattern RecognitionGas Pixel Detector; Polarimetry; X-ray Astronomy; X-ray opticsCondensed Matter PhysicsComputer Science ApplicationsApplied MathematicGas Pixel Detector; Polarimetry; X-ray Astronomy; X-ray optics; Electronic Optical and Magnetic Materials; Condensed Matter Physics; Computer Science Applications1707 Computer Vision and Pattern Recognition; Applied Mathematics; Electrical and Electronic EngineeringGas Pixel Detector; Polarimetry; X-ray Astronomy; X-ray optics; Electronic Optical and Magnetic Materials; Condensed Matter Physics; Computer Science Applications; Computer Vision and Pattern Recognition; Applied Mathematics; Electrical and Electronic EngineeringComputer Vision and Pattern RecognitionX-ray optic
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Ceftolozane/Tazobactam for Treatment of Severe ESBL-Producing

2020

Abstract Background Few data are reported in the literature about the outcome of patients with severe extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) infections treated with ceftolozane/tazobactam (C/T), in empiric or definitive therapy. Methods A multicenter retrospective study was performed in Italy (June 2016–June 2019). Successful clinical outcome was defined as complete resolution of clinical signs/symptoms related to ESBL-E infection and lack of microbiological evidence of infection. The primary end point was to identify predictors of clinical failure of C/T therapy. Results C/T treatment was documented in 153 patients: pneumonia was the most common diagnosis (n = 46…

medicine.medical_specialtyceftolozane/tazobactammedicine.medical_treatmentCRRTTazobactamEnterobacteralesEnterobacteraleInternal medicineCRRT; ESBL; Enterobacterales; ceftolozane/tazobactam; septic shockMajor ArticlemedicineClinical endpointRenal replacement therapybusiness.industrySeptic shockRetrospective cohort studyOdds ratiomedicine.diseaseCeftolozane/tazobactam; CRRT; Enterobacterales; ESBL; Septic shockAcademicSubjects/MED00290Infectious DiseasesOncologyESBLseptic shockCeftolozanebusinessEmpiric therapymedicine.drugOpen forum infectious diseases
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XIPE: the X-ray imaging polarimetry explorer

2013

arXiv:1309.6995v1.-- et al.

AstronomyAstrophysics::High Energy Astrophysical PhenomenaPolarimetryFOS: Physical sciencesAstrophysics7. Clean energy01 natural scienceslaw.inventionX-raySettore FIS/05 - Astronomia E Astrofisicalaw0103 physical sciencesPolarimetry010303 astronomy & astrophysicsInstrumentation and Methods for Astrophysics (astro-ph.IM)Solar and Stellar Astrophysics (astro-ph.SR)Astronomy X-ray PolarimetryPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)Solar flare[SDU.ASTR]Sciences of the Universe [physics]/Astrophysics [astro-ph]010308 nuclear & particles physics[SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]White dwarfAstronomy and AstrophysicsTorusMagnetic reconnectionPolarization (waves)Neutron starAstrophysics - Solar and Stellar Astrophysics13. Climate actionSpace and Planetary Science[SDU]Sciences of the Universe [physics]Astrophysics::Earth and Planetary AstrophysicsAstrophysics - High Energy Astrophysical PhenomenaAstrophysics - Instrumentation and Methods for AstrophysicsFlare
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