0000000000404745
AUTHOR
Manuel Martinez
Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis
PURPOSE: To describe data on epidemiology, microbiology, clinical characteristics and outcome of adult patients admitted in the intensive care unit (ICU) with secondary peritonitis, with special emphasis on antimicrobial therapy and source control. METHODS: Post hoc analysis of a multicenter observational study (Abdominal Sepsis Study, AbSeS) including 2621 adult ICU patients with intra-abdominal infection in 306 ICUs from 42 countries. Time-till-source control intervention was calculated as from time of diagnosis and classified into 'emergency' ( 6 h). Relationships were assessed by logistic regression analysis and reported as odds ratios (OR) and 95% confidence interval (CI). RESULTS: The…
Multidimensional optical sensing and imaging for displays, computational imaging, optical security, and healthcare
In this invited paper, we present an overview of our recently published work on 3D imaging, visualization and displays, including optical security using quantum imaging principles, 3D microscopy, healthcare, automated disease identification with 3D imaging, fatigue free augmented reality 3D glasses, and optical security and authentication using photon counting for IC inspection, polarimetric photon counting 3D imaging, and 3D human gesture recognition
Focus issue introduction: 3D image acquisition and display: technology, perception and applications.
This Feature Issue of Optics Express is organized in conjunction with the 2021 Optica (OSA) conference on 3D Image Acquisition and Display: Technology, Perception and Applications which was held virtually from 19 to 23, July 2021 as part of the Imaging and Sensing Congress 2021. This Feature Issue presents 29 articles which cover the topics and scope of the 2021 3D conference. This Introduction provides a summary of these articles.
Liquid crystal lens array for 3D microscopy and endoscope application
In this paper, we demonstrate two liquid crystal (LC) lens array devices for 3D microscope and 3D endoscope applications respectively. Compared with the previous 3D biomedical system, the proposed LC lens arrays are not only switchable between 2D and 3D modes, but also are able to adjust focus in both modes. The multi-function liquid crystal lens (MFLC-lens) array with dual layer electrode has diameter 1.42 mm, which is much smaller than the conventional 3D endoscope with double fixed lenses. The hexagonal liquid crystal micro-lens array (HLC-MLA) instead of fixed micro-lens array in 3D light field microscope can extend the effective depth of field from 60 um to 780 um. To achieve the LC le…
Antimicrobial Lessons From a Large Observational Cohort on Intra-abdominal Infections in Intensive Care Units
Severe intra-abdominal infection commonly requires intensive care. Mortality is high and is mainly determined by disease-specific characteristics, i.e. setting of infection onset, anatomical barrier disruption, and severity of disease expression. Recent observations revealed that antimicrobial resistance appears equally common in community-acquired and late-onset hospital-acquired infection. This challenges basic principles in anti-infective therapy guidelines, including the paradigm that pathogens involved in community-acquired infection are covered by standard empiric antimicrobial regimens, and second, the concept of nosocomial acquisition as the main driver for resistance involvement. I…