0000000000405698
AUTHOR
Dace Zvaniņa
showing 4 related works from this author
On the Formation and Desolvation Mechanism of Organic Molecule Solvates: A Structural Study of Methyl Cholate Solvates
2017
Solvate formation and the desolvation mechanism of 25 obtained methyl cholate solvates were rationalized using crystal structure analysis and study of the phase transformations. The facile solvate formation was determined to be associated with the possibility for more efficient packing in structures containing solvent molecules. Most of the obtained solvates crystallized in one of the six isostructural solvate groups, with solvent selection based on the solvent capability to provide particular intermolecular interactions along with appropriate size and shape. In crystal structures several different methyl cholate conformers were observed, as apparently more efficient packing could be achiev…
Holskābes metilestera solvātu iegūšana un desolvatācija Holskābes metilestera solvātu iegūšana un desolvatācija
2013
Holskābes metilestera solvātu iegūšana un desolvatācija. Zvaniņa D., darba vadītājs Mg.Chem. Bērziņš A. Bakalaura darbs, 56 lappuses, 28 attēli, 2 tabulas, 40 literatūras avoti, 3 pielikumi. Latviešu valodā. Darbā tika pagatavoti holskābes metilestera metanola, etanola, acetonitrila un nitrometāna solvāti, un ar dažādām metodēm tika mēģināts iegūt holskābes metilestera hidrātu. Ar pulvera rentgendifraktometru ir pārbaudīts vai iegūti vēlamie solvāti. Ar pulvera rentgendifraktometru, rentgendifraktometra termokameru un derivatogrāfu tika pētīts solvātu desolvatācijas mehānisms un karsēšanas laikā notiekošās fāžu pārejas. Ar derivatogrāfu tika analizēti holskābes metilestera metanola un etano…
Holskābes un tās atvasinājumu solvātu veidošanās un desolvatācijas mehānisms
2015
Holskābes un tās atvasinājumu solvātu veidošanās un desolvatācijas mehānisms. Zvaniņa D., darba vadītāji prof. Actiņš A., Mg.Chem. Bērziņs A. Maģistra darbs, 60 lappuses, 27 attēli, 6 tabulas, 47 literatūras avoti, 3 pielikumi. Latviešu valodā. Darbā tika pagatavots holskābes metilestera dimetilformamīda solvāts un, kristalizējot holskābes metilesteri no izo-propanola, n-propanola un izo-butilspirta, iegūta holskābes metilestera I polimorfā forma. Kristalizējot holskābi, henodeoksiholskābi un ursodeoksiholskābi no dažādiem organiskajiem šķīdinātājiem, tika iegūti holskābes etanola, metanola un acetonitrila solvāti un henodeoksiholskābes nitrometāna solvāts. Iegūtās cietās fāzes tika pārbaud…
Detailed Analysis of Packing Efficiency Allows Rationalization of Solvate Formation Propensity for Selected Structurally Similar Organic Molecules
2018
In structural study of seven bile acids it was identified that their propensity for solvate formation is directly related to the packing efficiency of the unsolvated phases: low packing index, voids, and unsatisfied hydrogen bonding lead to extensive solvate formation, whereas efficient packing leads to the opposite. This was determined to be caused by the presence of OH group attached to carbon C12. Solvate formation was determined to provide a noticeable improvement in the packing efficiency for compounds having ansolvates with inefficient packing.