Mollusk antimicrobial peptides A review from activity-based evidences to computer-assisted sequences

Antimicrobial peptides (AMPs) represent the most universal immune effectors. Molluscs constitute the second largest animal phylum, after Arthropods, in term of number of species. Only a negligible number has been investigated regarding AMPs. The choice of the species to be studied relied on their economical importance and availability. First studies on molluscan AMPs dated from 1996 and were based on biological activities of biochemical-purified fractions. Such approach released all the original structures we know, with biological activity sometimes different from one isoform to another. Then, molecular biology techniques were applied to molluscan AMPs starting in 1999. Complete screening o…

Molecular characterization of macrophage migration inhibitory factor (MIF) from mussel, Mytilus galloprovincialis

Multi target antimicrobial peptides from mussel and the paradox af ayster.

Functional differential hemocytes behaviour in the clearance of bacteria and humoral defense factors variability in Mytilus galloprovincialis

Hemocytes and humoral defense factors variability from different Mediterranean populations of Mytilus galloprovincialis

Molluscan antimicrobial peptides, a review from activity-based evidences to computer-assisted sequences

Antimicrobial peptides (AMPs) represent the most universal immune effectors. Molluscs constitute the second largest animal phylum, after Arthropods, in term of number of species. Only a negligible number has been investigated regarding AMPs. The choice of the species to be studied relied on their economical importance and availability. First studies on molluscan AMPs dated from 1996 and were based on biological activities of biochemical-purified fractions. Such approach released all the original structures we know, with biological activity sometimes different from one isoform to another. Then, molecular biology techniques were applied to molluscan AMPs starting in 1999. Complete screening o…

Variabilità genica dei peptidi antimicrobici: polimorfismo dell’mRNA della mitilina B di M. galloprovincialis

Individual variability and gene expression specificity of the mussel antifungal mytimycin (MytM)