Facio-auricle-vertebral spectrum (Goldenhar's syndrome): Clinical study of 10 pediatric patients

Goldenhar's syndrome - also known as facio-auricolo-vertebral spectrum - is due to a developmental defect of cranio-facial and vertebral structures, and is interpreted as a disruption. Exogenous factors, such as gestational diabetes or ovopathies, have been involved in its aetiology. The pathogenesis of Goldenhar's syndrome seems to be vascular in most of cases, due to the interruption of blood supply to the branchial and vertebral areas during embryonic development. Ten cases of facio-auricolo-vertebral spectrum of different ages are described, in view of a better delineation of its phenotype. This report can contribute to a better knowledge of the phenotype of facio-auricolo-vertebral spe…

Motivating factors of cephalalgia during the age of development: Personal experience

Clinical evolution of asthma from early childhood to development age

The aim of study was to conduct evaluation over twenty years on patients with relapsing wheezing breathing since their early years of life. The research included a period of observation started in 1978 up to 2002. The follow-up included 381 patients. The enrolment was carried out during the first 15 years, after being evaluated during outpatient or/ and hospitalization the children with a clinical picture resembling asthma (at least three episodes of dyspnea for a year, at least 2 years prior to our first observation). During follow-up the rhole of some risk factors in childhood able to affect the persistency of asthma in adulthood was considered. An early onset of symptoms resulted to be a…