0000000000406367

AUTHOR

Hein Stigum

showing 6 related works from this author

Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes

2019

Importance: Both low and high gestational weight gain have been associated with adverse maternal and infant outcomes, but optimal gestational weight gain remains uncertain and not well defined for all prepregnancy weight ranges. Objectives: To examine the association of ranges of gestational weight gain with risk of adverse maternal and infant outcomes and estimate optimal gestational weight gain ranges across prepregnancy body mass index categories. Design, setting, and participants: Individual participant-level meta-analysis using data from 196 670 participants within 25 cohort studies from Europe and North America (main study sample). Optimal gestational weight gain ranges were estimated…

Gestational hypertensionNutrition and Disease01 natural sciencesBody Mass Index0302 clinical medicinePregnancyVoeding en ZiekteMedicineBirth Weight030212 general & internal medicineObstetricsDiabetesPregnancy OutcomeGestational ageGeneral MedicineCesarean Section/statistics & numerical dataAdult; Birth Weight; Cesarean Section; Diabetes Gestational; Female; Humans; Hypertension Pregnancy-Induced; Infant Newborn; Obesity; Pregnancy; Premature Birth; Body Mass Index; Gestational Weight Gain; Pregnancy Complications; Pregnancy OutcomeGestational Weight GainGestational diabetesPremature birthGestationalHypertensionPremature BirthFemalemedicine.symptomUnderweightPREGNANT-WOMENAdultmedicine.medical_specialtyBirth weightPregnancy-InducedHealthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]03 medical and health sciencesAll institutes and research themes of the Radboud University Medical CenterLife ScienceHumansObesity0101 mathematicsbusiness.industryCesarean Section010102 general mathematicsInfant NewbornInfantHypertension Pregnancy-Inducedmedicine.diseaseNewbornReconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]BODY-MASS INDEXPregnancy ComplicationsDiabetes GestationalbusinessBody mass indexWeight gain
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Early Life Exposure to Perfluoroalkyl Substances (PFAS) and ADHD: A Meta-Analysis of Nine European Population-Based Studies

2020

Introduction: To date, the evidence for an association between perfluoroalkyl substances (PFAS) exposure and attention deficit and hyperactivity disorder (ADHD) is inconclusive. Objective: We investigated the association between early life exposure to perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA), and ADHD in a collaborative study including nine European population-based studies, encompassing 4,826 mother-child pairs. Methods: Concentrations of PFOS and PFOA were measured in maternal serum/plasma during pregnancy, or in breast milk, with different timing of sample collection in each cohort. We used a validated pharmacokinetic model of pregnancy and lactation to estimate…

MaleHealth Toxicology and MutagenesisReproductive health and childbirth010501 environmental sciencesToxicology01 natural sciencesMedical and Health SciencesCohort Studies0302 clinical medicinePregnancyMedicine2.2 Factors relating to the physical environment030212 general & internal medicineAetiologyChildPediatricFluorocarbonsEarly life3. Good healthPeer reviewMilkBreast FeedingMental HealthAlkanesulfonic AcidsMeta-analysisChild PreschoolPrenatal Exposure Delayed EffectsEnvironmental PollutantsFemaleCaprylatesHumanPopulationMEDLINEMothers03 medical and health sciencesEnvironmental healthmental disordersHumansPreschool0105 earth and related environmental sciencesMilk Humanbusiness.industryResearchPublic Health Environmental and Occupational HealthEuropean populationEnvironmental Exposurebiochemical phenomena metabolism and nutritionAttention Deficit Hyperactivity Disorder (ADHD)Attention Deficit Disorder with HyperactivityAttention deficitbusinessEnvironmental SciencesEnvironmental Health Perspectives
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Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta-analysis of European, …

2019

ObjectiveTo assess the separate and combined associations of maternal pre‐pregnancy body mass index (BMI) and gestational weight gain with the risks of pregnancy complications and their population impact.DesignIndividual participant data meta‐analysis of 39 cohorts.SettingEurope, North America, and Oceania.Population265 270 births.MethodsInformation on maternal pre‐pregnancy BMI, gestational weight gain, and pregnancy complications was obtained. Multilevel binary logistic regression models were used.Main outcome measuresGestational hypertension, pre‐eclampsia, gestational diabetes, preterm birth, small and large for gestational age at birth.ResultsHigher maternal pre‐pregnancy BMI and gesta…

Gestational hypertensionand promotion of well-beingNutrition and DiseaseBirthweightReproductive health and childbirthLow Birth Weight and Health of the NewbornCardiovascularMedical and Health SciencesDISEASECohort Studies0302 clinical medicine3123 Gynaecology and paediatricsRisk FactorsPregnancyVoeding en ZiekteInfant MortalityOdds RatioMedicineBirth Weight2.1 Biological and endogenous factorsEPIDEMIOLOGYwq_200Aetiology2. Zero hungerPediatricRISKeducation.field_of_studyOUTCOMES030219 obstetrics & reproductive medicineObstetricspregnancy complicationsDiabetesObstetrics and GynecologyGestational ageweight gainASSOCIATIONGestational Weight GainGestational diabetesEuropeBirthweight ; Body Mass Index ; Pregnancy Complications ; Preterm Birth ; Weight GainOBESITYFemalemedicine.symptomAdultmedicine.medical_specialtyPRETERM BIRTHBirth weightPopulationGestational Agebody mass index[SDV.MHEP.GEO]Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetricswa_310Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]03 medical and health sciencesAll institutes and research themes of the Radboud University Medical CenterPretermClinical ResearchHumanswq_100ObesityeducationObstetrics & Reproductive MedicineMetabolic and endocrineNutritionPregnancybusiness.industryContraception/ReproductionPreventionBirthweight; body mass index; pregnancy complications; preterm birth; weight gainAustraliaInfantbirth weightpreterm birthDIABETES-MELLITUSPreterm birth weight gainOverweightPerinatal Period - Conditions Originating in Perinatal Periodmedicine.diseaseNewbornPrevention of disease and conditionsReconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]Good Health and Well BeingNorth America3.1 Primary prevention interventions to modify behaviours or promote wellbeingpregnancy complicationbusinessWeight gainBody mass indexwb_200
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Prenatal and postnatal exposure to persistent organic pollutants and attention-deficit and hyperactivity disorder: a pooled analysis of seven Europea…

2018

International audience; Background - Attention-deficit/hyperactivity disorder (ADHD) is increasing worldwide for reasons largely unknown and environmental chemicals with neurotoxic properties, such as persistent organic pollutants (POPs), have been proposed to play a role. We investigated the association between prenatal and postnatal exposure to polychlorinated biphenyl-153 (PCB-153), p-p´-dichlorodiphenyldichloroethylene (p-p'-DDE) and hexachlorobenzene (HCB) and ADHD in childhood. Methods - We pooled seven European birth cohort studies encompassing 4437 mother-child pairs from the general population with concentrations of PCB-153, p-p´-DDE and HCB measured in cord blood, maternal blood o…

MaleEpidemiology010501 environmental sciences01 natural sciencesCohort Studies0302 clinical medicinePregnancyHexachlorobenzeneChildeducation.field_of_studyPerinatal ExposureGeneral MedicineEnvironmental exposureFetal BloodPolychlorinated Biphenyls3. Good healthEuropeMaternal ExposureChild PreschoolPrenatal Exposure Delayed EffectsEnvironmental PollutantsFemaleCohort studyAdolescentpolychlorinated biphenylsDichlorodiphenyl DichloroethylenePopulationPrenatal careattention-deficit disorder with hyperactivityDDT03 medical and health sciencesmedicineAttention deficit hyperactivity disorderHumanseducationPrenatal Exposures to Pollutants0105 earth and related environmental sciencesPregnancybusiness.industryOdds ratioEnvironmental Exposuremedicine.diseaseLogistic Modelshexachlorobenzene[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologieAttention Deficit Disorder with Hyperactivity[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiebusiness030217 neurology & neurosurgeryDemography
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Birth Weight and Prenatal Exposure to Polychlorinated Biphenyls (PCBs) and Dichlorodiphenyldichloroethylene (DDE): A Meta-analysis within 12 European…

2011

Abstract: Objectives: Exposure to high concentrations of persistent organochlorines may cause fetal toxicity, but the evidence at low exposure levels is limited. Large studies with substantial exposure contrasts and appropriate exposure assessment are warranted. Within the framework of the EU (European Union) ENRIECO (ENvironmental Health RIsks in European Birth Cohorts) and EU OBELIX (OBesogenic Endocrine disrupting chemicals: LInking prenatal eXposure to the development of obesity later in life) projects, we examined the hypothesis that the combination of polychlorinated biphenyls (PCBs) and dichlorodiphenyldichloroethylene (DDE) adversely affects birth weight. Methods: We used maternal a…

MaleHealth Toxicology and MutagenesisPhysiologyReview010501 environmental sciences01 natural sciencesCohort Studieschemistry.chemical_compound0302 clinical medicinePregnancyBirth Weight030212 general & internal medicinePCBsgestational ageSmokingGestational ageFetal BloodPolychlorinated Biphenyls3. Good healthEuropeChemistryDichlorodiphenyldichloroethyleneMeta-analysisToxicityDDE/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingEnvironmental PollutantsFemaleCohort studyAdultmedicine.medical_specialtyBirth weightDichlorodiphenyl Dichloroethylene03 medical and health sciencesYoung AdultSex Factorsbirth cohort studiesSDG 3 - Good Health and Well-beingInternal medicinemedicineHumansBiology0105 earth and related environmental sciencesPregnancyFetusMilk Humanbusiness.industryPublic Health Environmental and Occupational Healthmedicine.diseasemeta-analysisreproductive effectsEndocrinologychemistryLinear ModelsHuman medicinebusinessEnvironmental Health Perspectives
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Anthropometric measures of 9-to 10-year-old native tibetan children living at 3700 and 4300m above sea level and han Chinese living at 3700m

2015

A high residential altitude impacts on the growth of children, and it has been suggested that linear growth (height) is more affected than body mass. The aim of the present study was to estimate the prevalence of obesity, overweight, underweight, and stunting in groups of native Tibetan children living at different residential altitudes (3700 vs 4300 m above sea level) and across ancestry (native Tibetan vs Han Chinese children living at the same altitude of 3700 m), as well as to examine the total effect of residential altitude and ancestry with stunting. Two cross-sectional studies of 1207 school children aged 9 to 10 years were conducted in Lhasa in 2005 and Tingri in 2007. Conventional …

*altitude *anthropometry article body height body mass chest circumference child controlled study cross- sectional study diet dietary intake disease association disease severity female Han Chinese human major clinical study male *obesity/ep [Epidemiology] *obesity/et [Etiology] prevalence priority journal school child sex ratio social status *stunting/ep [Epidemiology] *stunting/et [Etiology] Tibetan (people) *underweight/ep [Epidemiology] *underweight/et [Etiology] waist circumference
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