0000000000406684
AUTHOR
S. Jung
Molecular switching complexes with iron and tin as central atom
Abstract The precursor [Fe III (L)Cl] (LH 2 = N , N ′-bis(2′-hydroxy-benzyliden)-1,6-diamino-3-N-hexane is a high-spin ( S = 5/2) complex. This precursor is combined with the bridging units [Sn IV (X) 4 ] (X = CN − , NCS − ) to yield star-shaped pentanuclear clusters, [(LFe III –X) 4 Sn]Cl 4 . For X = CN − the 57 Fe-Mossbauer data show a multiple spin transition between iron(III) in the high-spin and low-spin state, while the 119m Sn-Mossbauer data indicate a valence tautomerism between Sn(IV) and Sn(II). Changing the bridging unit from X = CN − to X = NCS − turns the switchability off.
Comparison between a guaiac and three immunochemical faecal occult blood tests in screening for colorectal cancer
Abstract Background The aim of this study was to compare the performance of the guaiac-based faecal occult blood test (G-FOBT), with that of three immunochemical faecal occult blood tests (I-FOBT) which allow automatic interpretation. Patients and methods Under the French organised screening programme, 85,149 average-risk individuals aged 50–74 participating in the third screening round, performed both the G-FOBT (Hemoccult-II test) and one of the I-FOBTs: FOB-Gold, Magstream and OC-Sensor. Results Given the chosen threshold, the positivity ratio between the different I-FOBTs and the G-FOBT was 2.4 for FOB-Gold, 2.0 for Magstream and 2.2 for OC-Sensor (P = 0.17). The three I-FOBTs were supe…
Mitochondrial DNA in the central european population
Sequencing of mtDNA is an advanced method for the individualisation of traces. Disadvantages of this method are expensive and time-consuming analysis and evaluation procedures as well as the necessary stock of population-genetic data which is still insufficient. Central European institutes of forensic medicine from Germany, Austria, and Switzerland have been working together since the beginning of 1998 to establish a mtDNA database. The aim is to build up a large stock of forensically established data and provide population-genetic data for frequency investigations, which will serve as a basis for expert opinions and scientific research. Good data quality is ensured by using original sequen…