0000000000407092
AUTHOR
Jaime García-rupérez
Peer-assessment using test exams in a Sakai-based e-learning platform
We report our work on the implementation of a learning innovation based on the combination of peer-assessment and formative learning. The methodology consists on the students themselves to propose, review and select questions for the subsequent creation of a "multiple choice" exam to assess their progress. This learning innovation is carried out with a minimum intervention from the lecturer by using testing tools from the Sakai-based e-learning platform of our institution in combination with several software functions that have been created to automate the aggregation and processing of the students’ contributions. According to the feedback collected from the students, these learning tasks h…
A Tetra-Panel of Serum Circulating miRNAs for the Diagnosis of the Four Most Prevalent Tumor Types
The purpose of this study is to clinically validate a series of circulating miRNAs that distinguish between the 4 most prevalent tumor types (lung cancer (LC)
Real-time and low-cost sensing technique based on photonic bandgap structures
[EN] A technique for the development of low-cost and high-sensitivity photonic biosensing devices is proposed and experimentally demonstrated. In this technique, a photonic bandgap structure is used as transducer, but its readout is performed by simply using a broadband source, an optical filter, and a power meter, without the need of obtaining the transmission spectrum of the structure; thus, a really low-cost system and real-time results are achieved. Experimental results show that it is possible to detect very low refractive index variations, achieving a detection limit below 2 x 10(-6) refractive index units using this low-cost measuring technique. (C) 2011 Optical Society of America[
Experimental Study of the Oriented Immobilization of Antibodies on Photonic Sensing Structures by Using Protein A as an Intermediate Layer
[EN] A proper antibody immobilization on a biosensor is a crucial step in order to obtain a high sensitivity to be able to detect low target analyte concentrations. In this paper, we present an experimental study of the immobilization process of antibodies as bioreceptors on a photonic ring resonator sensor. A protein A intermediate layer was created on the sensor surface in order to obtain an oriented immobilization of the antibodies, which enhances the interaction with the target antigens to be detected. The anti-bovine serum albumin (antiBSA)-bovine serum albumin (BSA) pair was used as a model for our study. An opto-fluidic setup was developed in order to flow the different reagents and,…
Measurement technique for real-time and low-cost biosensing using photonic bandgap structures
We present a sensing technique based on using photonic bandgap structures where only the output power is monitored, without the need of tunable sources or spectrum analyzers, thus providing a real-time and low-cost system.