0000000000407542

AUTHOR

Salvatore Lopez

0000-0001-7705-3715

showing 2 related works from this author

Target Therapies for Uterine Carcinosarcomas: Current Evidence and Future Perspectives

2017

Carcinosarcomas (CS) in gynecology are very infrequent and represent only 2–5% of uterine cancers. Despite surgical cytoreduction and subsequent chemotherapy being the primary treatment for uterine CS, the overall five-year survival rate is 30 ± 9% and recurrence is extremely common (50–80%). Due to the poor prognosis of CS, new strategies have been developed in the last few decades, targeting known dysfunctional molecular pathways for immunotherapy. In this paper, we aimed to gather the available evidence on the latest therapies for the treatment of CS. We performed a systematic review using the terms “uterine carcinosarcoma”, “uterine Malignant Mixed Müllerian Tumors”, “target therapies”,…

0301 basic medicineOncologyPathologyAngiogenesisCarcinosarcomas epigenetics genetics immunotherapy uterine cancer.medicine.medical_treatmentReviewEpigenesis Geneticlcsh:Chemistry0302 clinical medicineCarcinosarcomaAntibodies BispecificCarcinosarcomas Epigenetics Genetics Immunotherapy Uterine cancerMedicinegeneticsMolecular Targeted Therapylcsh:QH301-705.5Human Epidermal Growth Factor Receptor 2SpectroscopyNeovascularization PathologicGeneral MedicineEpithelial Cell Adhesion MoleculePrognosisComputer Science ApplicationsErbB ReceptorsSurvival Rate030220 oncology & carcinogenesisUterine NeoplasmsFemaleImmunotherapymedicine.medical_specialtyPoor prognosisMixed Tumor MullerianCatalysisuterine cancerInorganic Chemistry03 medical and health sciencesCancer stem cellInternal medicineBiomarkers TumorHumansTarget therapyPhysical and Theoretical ChemistrycarcinosarcomasMolecular BiologySurvival rateChemotherapyepigeneticsbusiness.industryOrganic ChemistryImmunotherapy030104 developmental biologylcsh:Biology (General)lcsh:QD1-999businessInternational Journal of Molecular Sciences
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Impact of covid-19 in gynecologic oncology: A nationwide italian survey of the sigo and mito groups

2020

Objective Coronavirus disease 2019 (COVID-19) has caused rapid and drastic changes in cancer management. The Italian Society of Gynecology and Obstetrics (SIGO), and the Multicenter Italian Trials in Ovarian cancer and gynecologic malignancies (MITO) promoted a national survey aiming to evaluate the impact of COVID-19 on clinical activity of gynecologist oncologists and to assess the implementation of containment measures against COVID-19 diffusion. Methods The survey consisted of a self-administered, anonymous, online questionnaire. The survey was sent via email to all the members of the SIGO, and MITO groups on April 7, 2020, and was closed on April 20, 2020. Results Overall, 604 particip…

International CooperationComputer-assisted web interviewingCOVID-19; Health Care Surveys; SARS-CoV-2 Infection; Surgical Oncology; Betacoronavirus; COVID-19; Coronavirus Infections; Female; Genital Neoplasms Female; Gynecologic Surgical Procedures; Gynecology; Humans; Infection Control; International Cooperation; Italy; Medical Oncology; Pandemics; Pneumonia Viral; SARS-CoV-2; Societies Medical; Surveys and Questionnaires; TriageMedical Oncology0302 clinical medicineGynecologic Surgical ProceduresSurgical oncologyGynecologic Surgical ProcedureSurveys and QuestionnairesPandemicHealth careMedicineInfection controlViralStatistics & numerical dataSurveySocieties Medical030219 obstetrics & reproductive medicineObstetrics and GynecologyGeneral MedicineSurgical OncologyOncologyItaly030220 oncology & carcinogenesisSARS-CoV-2 InfectionOriginal ArticleFemaleGenital NeoplasmsCoronavirus Infectionsmedicine.medical_specialtyGenital Neoplasms FemalePneumonia ViralGynecologic oncology03 medical and health sciencesBetacoronavirusMedicalHumansCOVID-19; Health Care Surveys; SARS-CoV-2 Infection; Surgical OncologyPandemicsInfection ControlBetacoronaviruPandemicbusiness.industryCoronavirus InfectionSARS-CoV-2COVID-19PneumoniaTriageSettore MED/40 - GINECOLOGIA E OSTETRICIAHealth Care SurveyGynecologyFamily medicineHealth Care SurveysTriagebusinessSocieties
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