0000000000409156

AUTHOR

Patricia Martel

showing 2 related works from this author

Influence of the amount of food ingested on mesolimbic dopaminergic system activity: a microdialysis study.

1996

Abstract The mesolimbic dopaminergic system (MDS) has been shown to be activated by ingestive behaviors, and it has been suggested that this activation may be related to the rewarding properties of foods. Because rats eat more when given a more palatable diet, this study was undertaken to determine the relationship between the amount of food ingested and DA release in the nucleus accumbens of freely moving rats. The extracellular levels of dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) were measured by high-performance liquid chromatography with electrochemical detection on microdialysis samples from the nucleus accumbens. Each rat underwent three microdia…

MaleMicrodialysismedicine.medical_specialtyDopamineMicrodialysisClinical BiochemistryNucleus accumbensBiologyToxicologyBiochemistryNucleus AccumbensRats Sprague-DawleyBehavioral Neurosciencechemistry.chemical_compoundEatingDopamineInternal medicinemedicineLimbic SystemAnimalsPalatabilityBiological PsychiatryPharmacologydigestive oral and skin physiologyHomovanillic acidDopaminergicHomovanillic Acidmedicine.diseaseRatsEndocrinologychemistryCatecholamine34-Dihydroxyphenylacetic AcidExtracellular SpaceIngestive behaviorsmedicine.drugPharmacology, biochemistry, and behavior
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Mesolimbic dopaminergic system activity as a function of food reward: A microdialysis study

1996

The mesolimbic dopaminergic system (MDS) has been shown to be implicated in feeding behaviors. The present experiment was conducted to examine the effects of the sensory properties of food ingested on MDS activity. Microdialysis coupled to high-performance liquid chromatography with electrochemical detection was employed to measure the extracellular levels of dopamine (DA) and its main metabolites (DOPAC and HVA) in the nucleus accumbens of freely moving rats. During microdialysis sessions rats had access or not to powdered foods varying in palatability: short cakes as highly palatable (HP) food and regular chow as low palatable (LP) food. In the absence of food, there were no alterations i…

Malemedicine.medical_specialtyMicrodialysisDopamineMicrodialysisClinical BiochemistryNucleus accumbensToxicologyBiochemistryNucleus AccumbensRats Sprague-DawleyBehavioral Neurosciencechemistry.chemical_compoundRewardDopamineInternal medicineLimbic SystemmedicineAnimalsIngestionPalatabilityNeurotransmitterBiological PsychiatryPharmacologydigestive oral and skin physiologyDopaminergicHomovanillic AcidRatsEndocrinologychemistryFoodCatecholamine34-Dihydroxyphenylacetic Acidmedicine.drugPharmacology Biochemistry and Behavior
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