0000000000413635

AUTHOR

Alessandro Agrillo

showing 2 related works from this author

Learning from experience. Proposal of a refined definition and staging system for bisphosphonate-related osteonecrosis of the jaw (BRONJ)

2012

Dear Editor, It is the authors’ belief that the internationally accepted definition of bisphosphonate-related osteonecrosis of the jaws (BRONJ) (Ruggiero et al, 2009) has several limitations that prevent clinicians from being confident with the diagnosis of the disease. Following recognition of the non-exposed BRONJ clinical variant (Lazarovici et al, 2009), we all became aware that the presence of ‘exposed necrotic bone in the oral cavity’, as outlined in the American Association of Oral and Maxillofacial Surgery (AAOMS) case definition, is just one of the possible clinical manifestations of BRONJ and is not found in all BRONJ patients. As ‘bone exposure’ is certainly not the initial sign …

medicine.medical_specialtyMedullary cavityBone diseaseBiopsymedicine.medical_treatmentSettore MED/29 - Chirurgia MaxillofaccialeDiagnosis DifferentialSettore MED/28 - Malattie OdontostomatologicheTerminology as TopicOral and maxillofacial pathologymedicineHumansGeneral DentistryBisphosphonate-associated osteonecrosis of the jawBone Density Conservation AgentsDiphosphonatesbusiness.industryDecision TreesBisphosphonatemedicine.diseaseSurgeryOtorhinolaryngologybisphosphonate-related osteonecrosis of the jawOral and maxillofacial surgeryBisphosphonate-Associated Osteonecrosis of the JawDifferential diagnosisOsteonecrosis of the jawbusiness
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Osteonecrosis of jaw (onj): impact of italian patients, and role of italian physicians, dentists, and researchers in the growing evidence of a “new” …

2012

Purpose: Osteonecrosis of jaw (ONJ) is an uncommon but severe complication observed mostly in patients treated with bisphosphonates (BPs) for bone metastases, myeloma, osteoporosis (so called BRONJ, Bisphosphonate-Related Osteonecrosis of Jaw), but also with other drugs (bevacizumab, sunitinib, denosumab). The number of cases observed in Italy appears high in comparison with other countries and we present a review of several aspects of ONJ in Italy and the role of Italian health professionals and researchers on increasing knowledge and adequate reporting of ONJ phenomenon; Methods: Literature review about osteonecrosis of jaw (ONJ) with selection of Italian authors and publications, on year…

medicine.medical_specialtybusiness.industryItalian languagemedicine.medical_treatmentOsteoporosisElectronic journalDentistrymedicine.diseaseDenosumabDental extractionNew diseasemedicineIn patientIntensive care medicinebusinessSevere complicationmedicine.drugWorking Paper of Public Health
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