0000000000415265

AUTHOR

Robert N Harden

showing 2 related works from this author

Validation of proposed diagnostic criteria (the "Budapest Criteria") for Complex Regional Pain Syndrome

2010

Current IASP diagnostic criteria for CRPS have low specificity, potentially leading to overdiagnosis. This validation study compared current IASP diagnostic criteria for CRPS to proposed new diagnostic criteria (the "Budapest Criteria") regarding diagnostic accuracy. Structured evaluations of CRPS-related signs and symptoms were conducted in 113 CRPS-I and 47 non-CRPS neuropathic pain patients. Discriminating between diagnostic groups based on presence of signs or symptoms meeting IASP criteria showed high diagnostic sensitivity (1.00), but poor specificity (0.41), replicating prior work. In comparison, the Budapest clinical criteria retained the exceptional sensitivity of the IASP criteria…

MaleValidation studymedicine.medical_specialtyDatabases FactualSigns and symptomsDiagnostic accuracySensitivity and SpecificityArticleDiagnosis DifferentialmedicineRegional pain syndromeHumansOverdiagnosisPain Measurementbusiness.industryReproducibility of ResultsComplex Regional Pain Syndrome Reflex sympathetic dystrophy CRPS RSD Diagnosis Validation reflex sympathetic dystrophy syndrome type-i signs crpsmedicine.diseaseSurgeryAnesthesiology and Pain MedicineComplex regional pain syndromeNeurologyPhysical therapyFemaleNeurology (clinical)businessComplex Regional Pain Syndromes
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Complex regional pain syndrome: evidence for warm and cold subtypes in a large prospective clinical sample.

2016

Limited research suggests that there may be Warm complex regional pain syndrome (CRPS) and Cold CRPS subtypes, with inflammatory mechanisms contributing most strongly to the former. This study for the first time used an unbiased statistical pattern recognition technique to evaluate whether distinct Warm vs Cold CRPS subtypes can be discerned in the clinical population. An international, multisite study was conducted using standardized procedures to evaluate signs and symptoms in 152 patients with clinical CRPS at baseline, with 3-month follow-up evaluations in 112 of these patients. Two-step cluster analysis using automated cluster selection identified a 2-cluster solution as optimal. Resul…

AdultMalemedicine.medical_specialtyDatabases FactualPopulationStatistical patternSigns and symptoms610 Medicine & health03 medical and health sciences0302 clinical medicine030202 anesthesiologyInternal medicinemedicineHumansIn patientProspective StudieseducationProspective cohort studyPain MeasurementInflammationeducation.field_of_studyPain durationbusiness.industry10051 Rheumatology Clinic and Institute of Physical MedicineMiddle Agedmedicine.diseaseAnesthesiology and Pain MedicineComplex regional pain syndrome2728 Neurology (clinical)PhenotypeNeurologyAnesthesia2808 Neurology10046 Balgrist University Hospital Swiss Spinal Cord Injury CenterFemaleNeurology (clinical)2703 Anesthesiology and Pain Medicinebusiness030217 neurology & neurosurgeryComplex Regional Pain SyndromesPain
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