0000000000422542

AUTHOR

Alessandra Cirino

showing 4 related works from this author

Characterisation of indeterminate focal breast lesions on grey-scale ultrasound: role of ultrasound elastography.

2011

PURPOSE: This study was undertaken to evaluate the role of ultrasound (US) elastography in characterising focal breast lesions classified as indeterminate on B-mode US. MATERIALS AND METHODS: Eighty-four focal breast lesions, 64 benign and 20 malignant (mean diameter, 15.1 mm), detected but not characterised on B-mode US in 72 women, Breast Imaging Reporting and Data System (BI-RADS) US category 3 (n=56) or category 4 (n=28), were studied with US elastography and classified in consensus by two radiologists according to a five-point colour scale. Sensitivity, specificity and positive and negative predictive values (PPV and NPV) of US elastography compared with conventional US were calculated…

Adultmedicine.medical_specialtyBreast NeoplasmsGrey scaleSensitivity and SpecificityDiagnosis DifferentialElasticity Imaging TechniquesPredictive Value of TestsmedicineUltrasound elastographyHumansRadiology Nuclear Medicine and imagingProspective StudiesNeuroradiologyAgedAged 80 and overmedicine.diagnostic_testbusiness.industryUltrasoundInterventional radiologyGeneral MedicineMiddle AgedElasticity Imaging TechniquesFemaleRadiologyElastographyUltrasonography MammaryBreast Ultrasound elastography Breast neoplasmsbusinessIndeterminateSettore MED/36 - Diagnostica Per Immagini E RadioterapiaAlgorithms
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Diagnostic performance of 2D-shear wave elastography in the diagnosis of breast cancer: a clinical appraisal of cutoff values

2022

Purpose To assess the role of 2D-shear wave elastography (2D-SWE) in differentiating benign from malignant focal breast lesions (FBLs), providing new vendor-specific cutoff values. Methods 158 FBLs (size: 3.5-50 mm) detected in 151 women (age: 21-87 years) were prospectively evaluated by means 2D-SWE. For each lesion, an expert radiologist assessed US BI-RADS category and calculated the following four 2D-SWE parameters: (1) elasticity maximum (E-max); (2) mean elasticity (E-mean); (3) minimum elasticity (E-min); (4) elasticity ratio (E-ratio). US-guided core-biopsy was considered as standard of reference for all the FBLs classified as BI-RADS 4 or 5. For each 2D-SWE parameter, the optimal c…

AdultAged 80 and overReproducibility of ResultsBreast NeoplasmsGeneral MedicineMiddle AgedSensitivity and SpecificityDiagnosis DifferentialYoung AdultElasticity imaging techniquesShear wave imagingHumansFemaleRadiology Nuclear Medicine and imagingUltrasonography MammaryBreastSettore MED/36 - Diagnostica Per Immagini E RadioterapiaAgedUltrasonography
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Focal breast lesion characterization according to the BI-RADS US lexicon: role of a computer-aided decision-making support

2018

Objectives: to assess the diagnostic performance of a computer-guided decision- making software (S-Detect) in the US characterization of focal breast lesions (FBLs), according to the radiologist's experience. Materials and Methods: 300 FBLs (size: 2.6-47.2 mm; mean: 13.2 mm) in 255 patients (mean age: 51 years) were prospectively assessed in consensus according to BIRADS US lexicon by two experienced radiologists without and with S-Detect; to evaluate intra and inter-observer agreement, the same 300 FBLs were independently evaluated by two residents at baseline and after 3 months. Results: 120/300 (40%) FBLs were malignant, 2/300 (0.7%) high-risk and 178/300 (59.3%) benign. Experts review s…

AdultMalemedicine.medical_specialtySupport Vector MachineAdolescentdiagnosisBI-RADSBreast lesionneoplasmsBreast NeoplasmsBI-RADSLexiconComputer aidedBreast Neoplasms MaleDecision Support Techniques030218 nuclear medicine & medical imagingDiagnosis Differential03 medical and health sciences0302 clinical medicinePredictive Value of TestsmedicineHumansRadiology Nuclear Medicine and imagingDiagnosis Computer-AssistedBreastBI-RADS; breast; computer aided; diagnosis; neoplasms; ultrasonographyAgedNeuroradiologyUltrasonographyAged 80 and overmedicine.diagnostic_testbusiness.industryInterventional radiologyGeneral MedicineMiddle Aged030220 oncology & carcinogenesisComputer-aidedNeoplasmFemaleUltrasonography MammaryRadiologyUltrasonographybusinessSettore MED/36 - Diagnostica Per Immagini E RadioterapiaDiagnosi
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Ultrasonographic Detection of Vascularity of Focal Breast Lesions: Microvascular Imaging Versus Conventional Color and Power Doppler Imaging.

2021

To compare microvascular flow imaging (MVFI) to conventional Color-Doppler (CDI) and Power-Doppler (PDI) imaging in the detection of vascularity of Focal Breast Lesions (FBLs). A total of 180 solid FBLs (size: 3.5–45.2 mm) detected in 180 women (age: 21–87 years) were evaluated by means of CDI, PDI, and MVFI. Two blinded reviewers categorized lesion vascularity in absent or present, and vascularity pattern as (a) internal; (b) vessels in rim; (c) combined. The presence of a “penetrating vessel” was assessed separately. Differences in vascularization patterns (chi2 test) and intra- and inter-observer agreement (Fleiss method) were calculated. ROC analysis was performed to assess performance…

AdultBreast Neoplasms01 natural sciencesSensitivity and Specificity030218 nuclear medicine & medical imagingDiagnosis Differential03 medical and health sciencessymbols.namesakePower dopplerYoung Adult0302 clinical medicineVascularity0103 physical sciencesmedicineHumansRadiology Nuclear Medicine and imagingBreastUltrasonography Doppler Color010301 acousticsAgedAged 80 and overRadiological and Ultrasound Technologybusiness.industryUltrasonography DopplerMiddle AgedROC CurvesymbolsFemalebreast Doppler imaging microvessels ultrasonographymedicine.symptomUltrasonographyNuclear medicinebusinessDoppler effectMicrovascular flowUltrasonic imaging
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