0000000000422548

AUTHOR

Mathias Wernbom

0000-0003-0411-3611

showing 5 related works from this author

Type 1 Muscle Fiber Hypertrophy after Blood Flow–restricted Training in Powerlifters

2018

PURPOSE: To investigate the effects of blood flow restricted resistance exercise (BFRRE) on myofiber areas (MFA), number of myonuclei and satellite cells (SC), muscle size and strength in powerlifters. METHODS Seventeen national level powerlifters (25+/-6 yrs [mean+/-SD], 15 men) were randomly assigned to either a BFRRE group (n=9) performing two blocks (week 1 and 3) of five BFRRE front squat sessions within a 6.5-week training period, or a conventional training group (Con; n=8) performing front squats at ~70% of one-repetition maximum (1RM). The BFRRE consisted of four sets (first and last set to voluntary failure) at ~30% of 1RM. Muscle biopsies were obtained from m. vastus lateralis (VL…

AdultMalemedicine.medical_specialtyMuscle sizeSatellite Cells Skeletal Musclemyonuclear domainkaatsuCell CountPhysical Therapy Sports Therapy and RehabilitationMicrocirculationYoung Adult03 medical and health sciences0302 clinical medicineInternal medicineHumansMedicineMyocyteOrthopedics and Sports MedicineNational levelMuscle StrengthMuscle SkeletalUltrasonographyCell NucleusKaatsubusiness.industryMicrocirculationResistance trainingResistance Training030229 sport sciencesBlood flowMuscle Fibers Slow-TwitchathletesEndocrinologyRegional Blood FlowRNAishemic trainingFemaleMuscle fiber hypertrophymyonuclear additionbusinessmyogenic stem cellsMedicine & Science in Sports & Exercise
researchProduct

Delayed myonuclear addition, myofiber hypertrophy, and increases in strength with high-frequency low-load blood flow restricted training to volitiona…

2018

The purpose of the present study was to investigate muscle hypertrophy, strength, and myonuclear and satellite cell (SC) responses to high-frequency blood flow-restricted resistance exercise (BFRRE). Thirteen individuals [24 ± 2 yr (mean ± SD), 9 men] completed two 5-day blocks of 7 BFRRE sessions, separated by a 10-day rest period. Four sets of unilateral knee extensions to voluntary failure at 20% of one repetition maximum (1RM) were conducted with partial blood flow restriction (90–100 mmHg). Muscle samples obtained before, during, 3 days, and 10 days after training were analyzed for muscle fiber area (MFA), myonuclei, SC, and mRNA and miRNA expression. Muscle size was measured by ultra…

AdultMalemedicine.medical_specialtyPhysiologyMuscle Fibers SkeletalMuscle hypertrophyYoung Adult03 medical and health sciences0302 clinical medicinePhysiology (medical)Internal medicineHumansLow loadMedicineMyocyteMuscle StrengthRNA MessengerExerciseKaatsubusiness.industryResistance trainingResistance TrainingHypertrophy030229 sport sciencesBlood flowRegional Blood FlowCardiologyFemalebusiness030217 neurology & neurosurgeryJournal of Applied Physiology
researchProduct

Frequent blood flow restricted training not to failure and to failure induces similar gains in myonuclei and muscle mass

2021

The purpose of the present study was to compare the effects of short-term high-frequency failure vs non-failure blood flow–restricted resistance exercise (BFRRE) on changes in satellite cells (SCs), myonuclei, muscle size, and strength. Seventeen untrained men performed four sets of BFRRE to failure (Failure) with one leg and not to failure (Non-failure; 30-15-15-15 repetitions) with the other leg using knee-extensions at 20% of one repetition maximum (1RM). Fourteen sessions were distributed over two 5-day blocks, separated by a 10-day rest period. Muscle samples obtained before, at mid-training, and 10-day post-intervention (Post10) were analyzed for muscle fiber area (MFA), myonuclei, an…

AdultMalemedicine.medical_specialtyTime FactorsSatellite Cells Skeletal MuscleRestPhysical ExertionSensationPhysical Therapy Sports Therapy and RehabilitationIsometric exercise030204 cardiovascular system & hematologyQuadriceps MuscleMuscle hypertrophy03 medical and health sciences0302 clinical medicineIsometric ContractionInternal medicineOne-repetition maximumHumansMedicineOrthopedics and Sports MedicineMuscle StrengthCreatine KinaseCell ProliferationUltrasonographyCell NucleusLegPalpationKaatsuElectromyographyMyoglobinbusiness.industryOvertrainingResistance TrainingMyalgiaOrgan Size030229 sport sciencesBlood flowmedicine.diseaseOverreachingVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850Muscle Fibers Slow-TwitchRegional Blood FlowCell Nucleus SizeMuscle Fibers Fast-TwitchCardiologybusinessSupercompensation
researchProduct

High-frequency blood flow-restricted resistance exercise results in acute and prolonged cellular stress more pronounced in type I than in type II fib…

2021

Myocellular stress with high-frequency blood flow-restricted resistance exercise (BFRRE) was investigated by measures of heat shock protein (HSP) responses, glycogen content, and inflammatory markers. Thirteen participants [age: 24 ± 2 yr (means ± SD), 9 males] completed two 5-day blocks of seven BFRRE sessions, separated by 10 days. Four sets of unilateral knee extensions to failure at 20% of one-repetition maximum (1RM) were performed. Muscle samples obtained before, 1 h after the first session in the first and second block (

0301 basic medicineAdultMalemedicine.medical_specialtyPhysiologyInflammationStress (mechanics)03 medical and health sciencesYoung Adult0302 clinical medicinePhysiology (medical)Internal medicinemedicineStress ProteinsHumansType i muscle fibersMuscle SkeletalExerciseKaatsuFiber typeChemistryResistance trainingResistance Training030229 sport sciencesBlood flowMicroRNAs030104 developmental biologyEndocrinologyMuscle Fibers Slow-TwitchRegional Blood FlowFemalemedicine.symptomJournal of applied physiology (Bethesda, Md. : 1985)
researchProduct

Risk of Muscle Damage With Blood Flow-Restricted Exercise Should Not Be Overlooked.

2019

medicine.medical_specialtybusiness.industryMusclesPhysical Therapy Sports Therapy and RehabilitationResistance TrainingBlood flowMuscle damageInternal medicinemedicineCardiologyHumansOrthopedics and Sports MedicinebusinessExerciseClinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine
researchProduct