showing 2 related works from this author
Precision wormlike nanoadjuvant governs potency of vaccination
2021
It remains unclear how the precise length of one-dimensional nanovehicles influences the characters of vaccination. Here, a unimolecular nanovehicle with tailored size and aspect ratio (AR) is applied to deliver CpG oligodeoxynucleotide, a Toll-like receptor (TLR) 9 agonist, as an adjuvant of recombinant hepatitis B virus surface antigen (rHBsAg), for treating chronic hepatitis B (CHB). Cationic nanovehicles with fixed width (ca. 45 nm) but varied length (46 nm-180 nm), AR from 1 to 4, are prepared through controlled polymerization and are loaded with CpG by electrostatic interaction. We reveal that the nanoadjuvant with AR = 2 shows the highest retention in proximal lymph nodes. Importantl…
On the classification of mapping class actions on Thurston's asymmetric metric
2011
AbstractWe study the action of the elements of the mapping class group of a surface of finite type on the Teichmüller space of that surface equipped with Thurston's asymmetric metric. We classify such actions as elliptic, parabolic, hyperbolic and pseudo-hyperbolic, depending on whether the translation distance of such an element is zero or positive and whether the value of this translation distance is attained or not, and we relate these four types to Thurston's classification of mapping class elements. The study is parallel to the one made by Bers in the setting of Teichmüller space equipped with Teichmüller's metric, and to the one made by Daskalopoulos and Wentworth in the setting of Te…