0000000000423274

AUTHOR

Javier Zurriaga

showing 3 related works from this author

IFT46 Expression in the Nasal Mucosa of Primary Ciliary Dyskinesia Patients: Preliminary Study

2021

Este artículo se encuentra disponible en la siguiente URL: https://journals.sagepub.com/doi/pdf/10.1177/2152656721989288 Background: Primary ciliary dyskinesia (PCD) is characterised by an imbalance in mucociliary clearance leading to chronic respiratory infections. Cilia length is considered to be a contributing factor in cilia movement. Recently, IFT46 protein has been related to cilia length. Therefore, this work aims to study IFT46 expression in a PCD patients cohort and analyse its relationship with cilia length and function, as it was not previously described. Materials and methods: The expression of one intraflagellar transport (IFT46) and two regulating ciliary architecture (FOXJ1 a…

lcsh:Immunologic diseases. Allergy0301 basic medicinePathologymedicine.medical_specialtyMucociliary clearanceCiliary dyskinesiaprimary ciliary dyskinesiaMucous membrane of noseCiliopathies03 medical and health sciences0302 clinical medicineKartagener's syndrome - Genetic aspects.Ciliogenesisotorhinolaryngologic diseasesmedicineImmunology and AllergyAparato respiratorio - Enfermedades.Original Research ArticleOtorrinolaringología.Respiratory systemPrimary ciliary dyskinesiaDisquinesia ciliar Síndrome de - Aspectos genéticos.IFT46business.industryCiliumRespiratory organs - Diseases.Kartagener Síndrome de - Aspectos genéticos.respiratory systemlcsh:OtorhinolaryngologyChronic diseases.medicine.diseaselcsh:RF1-547Otolaryngology.Enfermedades crónicas.030104 developmental biology030228 respiratory systemOtorhinolaryngologyPrimary ciliary dyskinesia - Genetic aspects.cilia lengthciliopathieslcsh:RC581-607businessciliogenesisAllergy & Rhinology
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In Vivo Articular Cartilage Regeneration Using Human Dental Pulp Stem Cells Cultured in an Alginate Scaffold: A Preliminary Study

2017

Osteoarthritis is an inflammatory disease in which all joint-related elements, articular cartilage in particular, are affected. The poor regeneration capacity of this tissue together with the lack of pharmacological treatment has led to the development of regenerative medicine methodologies including microfracture and autologous chondrocyte implantation (ACI). The effectiveness of ACI has been shown in vitro and in vivo, but the use of other cell types, including bone marrow and adipose-derived mesenchymal stem cells, is necessary because of the poor proliferation rate of isolated articular chondrocytes. In this investigation, we assessed the chondrogenic ability of human dental pulp stem c…

0301 basic medicinelcsh:Internal medicineArticle SubjectChemistryCartilageRegeneration (biology)0206 medical engineeringMesenchymal stem cell02 engineering and technologyCell BiologyAnatomyChondrogenesis020601 biomedical engineeringCell biology03 medical and health sciences030104 developmental biologymedicine.anatomical_structureDental pulp stem cellsmedicinelcsh:RC31-1245Autologous chondrocyte implantationMolecular BiologyAggrecanStem cell transplantation for articular cartilage repairResearch ArticleStem Cells International
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Optimization of a decellularized protocol of porcine tracheas. Long-term effects of cryopreservation. A histological study

2021

[EN] Objective: The aim of this study was to optimize a decellularization protocol in the trachea of Sus scrofa domestica (pig) as well as to study the effects of long-term cryopreservation on the extracellular matrix of decellularized tracheas. Methods: Porcine tracheas were decellularized using Triton X-100, SDC, and SDS alone or in combination. The effect of these detergents on the extracellular matrix characteristics of decellularized porcine tracheas was evaluated at the histological, biomechanical, and biocompatibility level. Morphometric approaches were used to estimate the effect of detergents on the collagen and elastic fibers content as well as on the removal of chondrocytes from …

OctoxynolSwine0206 medical engineeringTracheal stenosisBiomedical EngineeringMedicine (miscellaneous)Bioengineering02 engineering and technologyCryopreservationBiomaterialsAndrology03 medical and health sciences0302 clinical medicineMedicineSDSCryopreservationDecellularizationTissue EngineeringTissue Scaffoldsbusiness.industryTracheal histologyDecellularized tracheasAirway tissue engineeringGeneral Medicine020601 biomedical engineeringTracheal StenosisSus scrofa domesticaExtracellular MatrixTrachea030220 oncology & carcinogenesisFISICA APLICADAbusiness
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