0000000000424175

AUTHOR

Randolf Brehler

showing 3 related works from this author

Efficacy and safety of omalizumab in patients with chronic urticaria who exhibit IgE against thyroperoxidase

2011

Background A subgroup of patients with chronic spontaneous urticaria (CU) exhibits IgE antibodies directed against autoantigens, such as thyroperoxidase (TPO). We conducted this study to investigate whether such patients with CU with IgE against TPO benefit from treatment with omalizumab, a humanized anti-IgE mAb licensed for the treatment of severe persistent allergic (IgE-mediated) asthma. Objectives We sought to assess the efficacy of omalizumab treatment in patients with CU with IgE autoantibodies against TPO. Methods In this multicenter, randomized, double-blind, placebo-controlled study patients with CU (male/female, 18-70 years of age) with IgE autoantibodies against TPO who had pers…

AdultMalemedicine.medical_specialtyAdolescentUrticariamedicine.medical_treatmentImmunologyOmalizumabOmalizumabAntibodies Monoclonal HumanizedImmunoglobulin EPlaceboAutoantigensGastroenterologylaw.inventionYoung AdultRandomized controlled triallawInternal medicineAnti-Allergic AgentsmedicineHumansImmunology and AllergyAdverse effectAgedAutoantibodiesAsthmabiologybusiness.industryAntibodies MonoclonalImmunoglobulin EMiddle Agedmedicine.diseaseAntibodies Anti-IdiotypicTolerabilityImmunologybiology.proteinFemaleAntihistaminebusinessmedicine.drugJournal of Allergy and Clinical Immunology
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Blindness, tetraspasticity, and other signs of irreversible brain damage in hereditary angioedema

2017

Pulmonary and Respiratory MedicineAdultMalemedicine.medical_specialtyAdolescentImmunologyBrain damageLaryngeal EdemaBlindness03 medical and health sciences0302 clinical medicinemedicineImmunology and AllergyHumans030212 general & internal medicineHypoxia BrainBlindnessHereditary Angioedema Types I and IIbusiness.industryLaryngeal Edemamedicine.diseaseDermatologyMuscle SpasticityHereditary angioedemamedicine.symptombusiness030217 neurology & neurosurgery
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Recommendations for photopatch testing by the Photopatch Test Working Group of the German Contact Dermatitis Research Group (DKG).

2018

medicine.medical_specialtybusiness.industryDermatitis PhotoallergicPhotopatch testDermatologyPatch Testsmedicine.diseaseDermatologylanguage.human_languageGerman030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineGroup (periodic table)030220 oncology & carcinogenesislanguageMedicineHumansbusinessContact dermatitisJournal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
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