0000000000424977

AUTHOR

Philip W. Lavori

showing 3 related works from this author

Center differences and cross-national invariance in help-seeking for panic disorder. A report from the cross-national collaborative panic study.

1992

Help-seeking behaviour for treatment of panic disorder was investigated in the sample of the Cross-National Collaborative Panic Study Second Phase. A total of 1168 patients were entered into this trial in 14 countries. Although there were significant center differences in prior treatment and utilization of health services there were also similarities. Treatment had been provided mainly by general practitioners. Drug treatment consisted mostly of prescription of classical tranquilizers and had a longer duration than treatment by psychotherapy. Patients with agoraphobic avoidance, past major depression and longer duration of illness used medical and psychiatric treatment facilities more inten…

AdultCross-Cultural ComparisonMalemedicine.medical_specialtyImipramineHealth (social science)Social PsychologyEpidemiologyPharmacotherapyEpidemiologymedicineHumansMedical prescriptionPsychiatryDepression (differential diagnoses)Alprazolambusiness.industryPanic disorderIncidencePanicPatient Acceptance of Health Caremedicine.diseaseHelp-seekingPsychiatry and Mental healthCross-Sectional StudiesPanic DisorderFemalemedicine.symptombusinessAnxiety disorderClinical psychologySocial psychiatry and psychiatric epidemiology
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Chronology of panic and avoidance, age of onset in panic disorder, and prediction of treatment response. A report from the Cross-National Collaborati…

1991

The relevance of the chronology between panic disorder and avoidance behavior and of an early, medium or late onset of panic disorder was tested. Groups from the sample of the cross-national collaborative panic study (CNCPS) were compared for differences in basic characteristics and for the ability to predict treatment response. Patients who developed avoidance behavior before the full syndrome of panic disorder had less often a full agoraphobia but were not different in their response to treatment. Patients with an early onset of panic disorder suffered more often from agoraphobia. The treatment response was similar in the groups with early, medium or late onset of panic disorder. Neither …

AdultMalePersonality Testsmedicine.medical_specialtyImipramineLate onsetbehavioral disciplines and activitiesImipramineDrug Administration Schedulelaw.inventionRandomized controlled triallawmental disordersmedicineHumansPharmacology (medical)PsychiatryBiological PsychiatryAlprazolamGeneral NeurosciencePanic disorderAge FactorsPanicGeneral MedicineMiddle Agedmedicine.diseasePrognosisAnxiety DisordersPanichumanitiesPsychiatry and Mental healthNeuropsychology and Physiological PsychologyAlprazolamFemalemedicine.symptomAge of onsetPsychologyArousalmedicine.drugClinical psychologyAgoraphobiaEuropean archives of psychiatry and clinical neuroscience
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Avoidance behaviour: A predictor of the efficacy of pharmacotherapy in panic disorder?

1991

The impact of the avoidance behaviour on the psychopharmacological treatment of panic disorder was explored in the Cross National Collaborative Panic Study (n = 1134 patients); in this double blind randomized trial alprazolam, imipramine and placebo were compared during an 8-week treatment period. Patients with extensive avoidance behaviour (agoraphobia) had the most profit from the active drugs. Counter expectancy these specific drug effects were most pronounced in avoidance behaviour. Active drugs (in particular imipramine) were especially more effective than placebo if the patients presented with associated avoidance behaviour. The results suggest that agoraphobia defines more a particul…

AdultMalePersonality TestsImipraminemedicine.medical_specialtyPlacebobehavioral disciplines and activitiesImipraminelaw.inventionDouble-Blind MethodRandomized controlled triallawmental disordersmedicineHumansPharmacology (medical)Social BehaviorPsychiatryAgoraphobiaBiological PsychiatryAlprazolamPanic disorderPanicFearGeneral Medicinemedicine.diseasePanichumanitiesPsychiatry and Mental healthAlprazolamPanic DisorderFemalemedicine.symptomArousalPsychologyAnxiety disordermedicine.drugAgoraphobiaClinical psychologyEuropean Archives of Psychiatry and Clinical Neuroscience
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