0000000000427282

AUTHOR

Diaz Ana

showing 2 related works from this author

Early reductive stress followed by a late onset oxidative stress in acute myocardial infarction

2018

Introduction The idea that the cells might suffer from reductive rather than oxidative stress and that such stress may be relevant in pathophysiology has gained momentum. Aim We aimed at studying markers of oxidative stress and damage as well as the expression of antioxidant enzymes in a swine model of acute myocardial infarction (AMI) followed by reperfusion. Results and Discussion We found an increase in the GSH to GSSG ratio, a decrease in protein glutathionylation and a decrease in p38 MAPK phosphorylation after 90 minutes of ischaemia in heart samples. It was accompanied by an increase in the expression of Thioredoxin (TrX) and Peroxiredoxin (PrX) and a decrease in the expression of Gl…

chemistry.chemical_classificationmedicine.medical_specialtyProtein CarbonylationGlutathione peroxidaseGlutathione reductaseGlutathioneProtein glutathionylationmedicine.disease_causeBiochemistryLipid peroxidationchemistry.chemical_compoundEndocrinologychemistryPhysiology (medical)Internal medicinemedicineThioredoxinOxidative stressFree Radical Biology and Medicine
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Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

2020

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347

MaleOriginalmedicine.medical_treatmentartificialCritical Care and Intensive Care MedicineMedical and Health SciencesPressure ulcerlaw.inventionDecubitus epidemiology; ICU; Morbidity; Mortality; Outcome; Pressure injury; Pressure ulcer; Risk factors; Adult; Aged; Hospital Mortality; Humans; Male; Patient Discharge; Prevalence; Risk Factors; Intensive Care Units; Respiration Artificial0302 clinical medicineDecubitus epidemiologydecubitus epidemiology ; ICU ; pressure injury ; pressure ulcer ; outcome ; risk factors ; morbidity ; mortalitylawMedicine and Health SciencesadultsPrevalenceMedicineHospital MortalitySimplified Acute Physiology Scoredecubitus epidemiology; icu; pressure injury; pressure ulcer; outcome; risk factors; morbidityziekenhuissterfteImmunodeficiencyintensive careOutcomeEuropean Society of Intensive Care Medicine (ESICM) Trials Group CollaboratorsmannenvolwassenenCOSTIntensive care unitSTATEPatient DischargeIntensive Care UnitsULCERSUnderweightmedicine.symptomLife Sciences & BiomedicineDecubitus epidemiology; ICU; Morbidity; Mortality; Outcome; Pressure injury; Pressure ulcer; Risk factorsHumanAdultmedicine.medical_specialtyrisicofactorenDecubitus epidemiology ICU Pressure injury Pressure ulcer Outcome Risk factors Morbidity Mortalitypressure injuriesIntensive Care UnitprevalentieNO1117 Public Health and Health ServicesDecubICUs Study Team03 medical and health sciencesCritical Care MedicineAnesthesiologyGeneral & Internal MedicineHealth SciencesouderenHumansMortalityAgedMechanical ventilationScience & Technologybusiness.industrydecubitusRisk Factor030208 emergency & critical care medicine1103 Clinical SciencesOdds ratiomedicine.diseaseRespiration ArtificialEmergency & Critical Care MedicineConfidence interval030228 respiratory systemRisk factorsEmergency medicineICUkunstmatige ademhalingRISK-FACTORSMorbiditybusinessPressure injuryrespiration
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