Enhanced Oxidative Stress and Other Potential Biomarkers for Retinopathy in Type 2 Diabetics: Beneficial Effects of the Nutraceutic Supplements

We have studied the global risk of retinopathy in a Mediterranean population of type 2 diabetes mellitus (T2DM) patients, according to clinical, biochemical, and lifestyle biomarkers. The effects of the oral supplementation containing antioxidants/omega 3 fatty acids (A/ω3) were also evaluated. Suitable participants were distributed into two main groups: (1) T2DMG (with retinopathy (+DR) or without retinopathy (−DR)) and (2) controls (CG). Participants were randomly assigned (+A/ω3) or not (−A/ω3) to the oral supplementation with a daily pill of Nutrof Omega (R) for 18 months. Data collected including demographics, anthropometrics, characteristics/lifestyle, ophthalmic examination (best cor…

Biomarcadores de peroxidación lipídica en el humor acuoso de pacientes con glaucoma primario de ángulo abierto

Resumen Objetivo Investigamos la peroxidacion lipidica (PEROX) en el glaucoma primario de angulo abierto (GPAA) y si este mecanismo puede relacionarse con su progresion. Material y metodos Estudio prospectivo observacional, transversal, analitico no experimental de casos y grupo comparativo, con seleccion de 175 pacientes quirurgicos, distribuidos en: 1) grupo diagnosticado de GPAA (GG; n = 88) y 2) grupo comparativo de pacientes con cataratas (GC; n = 87). Se han obtenido datos demograficos, caracteristicas de los participantes y estilo de vida. Se realizo un examen oftalmologico centrado en GPAA. Se obtuvieron muestras de humor acuoso al principio de la cirugia programada, que fueron proc…

Biomarkers of lipid peroxidation in the aqueous humor of primary open-angle glaucoma patients

Objective To investigate the lipid peroxidation (PEROX) processes in primary open-angle glaucoma (POAG) patients, and whether this mechanism may be related to disease progression. Material and methods A prospective, observational, cross-sectional, non-experimental, and analytical study was conducted on a case and a comparison group, consisting of 175 surgical patients divided into: (1) POAG group (GG; n = 88) and (2) comparison group of patients with cataracts (CG; n = 87). Demographic data, patient characteristics, lifestyle data, as well as ophthalmological examination were registered in an Excel spreadsheet. Biochemical data were obtained by processing the aqueous humor collected at the …

MicroRNAs as potential biomarkers of eye diseases