0000000000434889

AUTHOR

Fernando San Juan

showing 3 related works from this author

Milan-out Criteria and Worse Intention-to-Treat Outcome Postliver Transplantation

2019

Background. Milan criteria are widely used for liver transplantation selection in hepatocellular carcinoma but have been recognized to be too restrictive. Milan-out criteria are increasingly being adopted. Our aim was to analyze if liver transplantation waitlisted Milan-out hepatocellular carcinoma patients have different outcome than Milan patients. Methods. Retrospective study including all consecutive patients with hepatocellular carcinoma admitted in the waiting list for liver transplantation between January 2012 and January 2015. We included 177 patients, 146 of which eventually transplanted. Downstaging was achieved in the Milan-out cases (n = 29) before waitlisting. Results. From dia…

Transplantationmedicine.medical_specialtyIntention-to-treat analysisbusiness.industrymedicine.medical_treatmenteducationHazard ratiolcsh:SurgeryRetrospective cohort studylcsh:RD1-811030230 surgeryMilan criteriaLiver transplantationmedicine.diseaseConfidence intervalLiver TransplantationTransplantation03 medical and health sciences0302 clinical medicineInternal medicineHepatocellular carcinomamedicine030211 gastroenterology & hepatologybusinessTransplantation Direct
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Long-term outcome of ‘long-term liver transplant survivors’

2013

There are few studies focusing on long-term complications in liver transplant (LT) recipients. The aim of this study was to define the outcome of LT recipients having survived at least 10 years from LT. Of 323 adult LT done between 1991 and 1997, the 167(52%) alive >10 years post-LT (baseline time) formed the study population. Long-term outcome measures included the following: immunosuppression, metabolic complications [obesity, arterial hypertension (AH), diabetes, dislypidemia], cardiovascular events (CVE), chronic renal dysfunction-CRD, and de novo tumors. Median age at LT was 50 years. Most common indication was postnecrotic cirrhosis (89%), mostly because of HCV (46%). At study-baselin…

AdultMalemedicine.medical_specialtyAdolescentmedicine.medical_treatmentLiver transplantationPostnecrotic cirrhosisRisk FactorsCause of DeathInternal medicineDiabetes mellitusmedicineHumansSurvivorsAgedRetrospective StudiesCause of deathTransplantationbusiness.industryImmunosuppressionRetrospective cohort studyMiddle Agedmedicine.diseaseObesityLiver TransplantationSurgeryTreatment OutcomePopulation studyFemalebusinessTransplant International
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Framingham score, renal dysfunction, and cardiovascular risk in liver transplant patients

2015

Cardiovascular (CV) events represent major impediments to the long-term survival of liver transplantation (LT) patients. The aim of this study was to assess whether the Framingham risk score (FRS) at transplantation can predict the development of post-LT cardiovascular events (CVEs). Patients transplanted between 2006 and 2008 were included. Baseline features, CV risk factors, and CVEs occurring after LT (ischemic heart disease, stroke, heart failure, de novo arrhythmias, and peripheral arterial disease) were recorded. In total, 250 patients (69.6% men) with a median age of 56 years (range, 18-68 years) were included. At transplantation, 34.4%, 34.4%, and 33.2% of patients, respectively, ha…

AdultMalemedicine.medical_specialtyTime FactorsAdolescentmedicine.medical_treatmentRenal functionKaplan-Meier EstimateLiver transplantationKidneyRisk AssessmentGastroenterologyYoung AdultRisk FactorsInternal medicinemedicineHumansAgedProportional Hazards ModelsRetrospective StudiesTransplantationUnivariate analysisFramingham Risk ScoreHepatologybusiness.industryProportional hazards modelHazard ratioHepatitis CMiddle Agedmedicine.diseaseHepatitis CTransplant RecipientsLiver TransplantationSurgeryTransplantationLogistic ModelsTreatment OutcomeCardiovascular DiseasesSpainMultivariate AnalysisFemaleKidney DiseasesSurgerybusinessGlomerular Filtration Rate
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