0000000000436017

AUTHOR

Kate Northstone

showing 15 related works from this author

Additional file 5 of Cross-sectional and longitudinal associations of active travel, organised sport and physical education with accelerometer-assess…

2022

Additional file 5.

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Additional file 10 of Cross-sectional and longitudinal associations of active travel, organised sport and physical education with accelerometer-asses…

2022

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Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM conso…

2015

To identify genetic variants associated with refractive astigmatism in the general population, meta-analyses of genome-wide association studies were performed for: White Europeans aged at least 25 years (20 cohorts, N = 31,968); Asian subjects aged at least 25 years (7 cohorts, N = 9,295); White Europeans aged <25 years (4 cohorts, N = 5,640); and all independent individuals from the above three samples combined with a sample of Chinese subjects aged <25 years (N = 45,931). Participants were classified as cases with refractive astigmatism if the average cylinder power in their two eyes was at least 1.00 diopter and as controls otherwise. Genome-wide association analysis was carried out for …

MaleRefractive errorBLUE MOUNTAINS EYECORNEAL ASTIGMATISMSpherical equivalentGenome-wide association studyastigmatism; gene; SNPDISEASECohort Studies0302 clinical medicineStatisticsGenetics(clinical)Neural Cell Adhesion MoleculesPOPULATIONGenetics (clinical)Original InvestigationGenetics0303 health scienceseducation.field_of_studyAge FactorsHigh Mobility Group ProteinsMiddle Aged3142 Public health care science environmental and occupational health3. Good healthFemaleOPEN-ANGLE GLAUCOMAAdultGenetic MarkersEXPERIMENTALLY-INDUCED MYOPIAKeratoconusSUSCEPTIBILITY LOCICell Adhesion Molecules NeuronaleducationPopulationNerve Tissue ProteinsAstigmatismBiologyWhite People03 medical and health sciencesAGEAsian PeopleMAJOR LOCUSmedicineGeneticsHumans3125 Otorhinolaryngology ophthalmologyeducation030304 developmental biologyGenetic associationCalcium-Binding ProteinsAstigmatismHeritabilitymedicine.diseaseNONCODING RNAS030221 ophthalmology & optometryGenome-Wide Association Study
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The multivariate physical activity signature associated with metabolic health in children and youth: An International Children's Accelerometry Databa…

2020

There is solid evidence for an association between physical activity and metabolic health outcomes in children and youth, but for methodological reasons most studies describe the intensity spectrum using only a few summary measures. We aimed to determine the multivariate physical activity intensity signature associated with metabolic health in a large and diverse sample of children and youth, by investigating the association pattern for the entire physical intensity spectrum. We used pooled data from 11 studies and 11,853 participants aged 5.8–18.4 years included in the International Children's Accelerometry Database. We derived 14 accelerometry-derived (ActiGraph) physical activity variabl…

Multivariate statisticsIntensityMetabolic risk factorsAdolescentEpidemiologyPhysical activityPattern analysisBlood Pressure610 Medicine & healthcomputer.software_genre01 natural sciences03 medical and health sciences0302 clinical medicineVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Pediatri: 760Multivariate pattern analysisAccelerometryMedicineHumansPooled data030212 general & internal medicine0101 mathematicsChildExerciseMetabolic healthchildhoodSedentary timePediatricDatabasebusiness.industry010102 general mathematicsPublic Health Environmental and Occupational Health10060 Epidemiology Biostatistics and Prevention Institute (EBPI)2739 Public Health Environmental and Occupational Healthmetabolic risk factorsVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850ChildhoodPeer reviewAccelerometeraccelerometerpediatricICADMulticollinearityInsulin ResistanceSedentary Behaviormultivariate pattern analysisbusinessintensitycomputer2713 Epidemiology
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Birth weight, cardiometabolic risk factors and effect modification of physical activity in children and adolescents: pooled data from 12 internationa…

2020

Abstract Objectives Low and high birth weight is associated with higher levels of cardiometabolic risk factors and adiposity in children and adolescents, and increases the risk of cardiovascular diseases, obesity, and early mortality later in life. Moderate-to-vigorous physical activity (MVPA) is associated with lower cardiometabolic risk factors and may mitigate the detrimental consequences of high or low birth weight. Thus, we examined whether MVPA modified the associations between birth weight and cardiometabolic risk factors in children and adolescents. Methods We used pooled individual data from 12 cohort- or cross-sectional studies including 9,100 children and adolescents. Birth weigh…

WaistAdolescentEpidemiologyEndocrinology Diabetes and MetabolismBirth weightMedicine (miscellaneous)Blood Pressure610 Medicine & health030209 endocrinology & metabolism03 medical and health sciences0302 clinical medicinemedicineBirth WeightHumans030212 general & internal medicineChildExerciseTriglyceridesAdiposityCardiometabolic riskNutrition and DieteticsNorwaybusiness.industryCholesterol HDLarticleCardiometabolic Risk FactorsPaediatrics2701 Medicine (miscellaneous)10060 Epidemiology Biostatistics and Prevention Institute (EBPI)medicine.diseaseVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850/692/700/478/174ObesityPeer review2712 Endocrinology Diabetes and MetabolismLow birth weightBlood pressureRisk factorsCohort2916 Nutrition and Dietetics/692/700/1720Waist Circumferencemedicine.symptombusinesshuman activities/692/499Demography
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Additional file 2 of Cross-sectional and longitudinal associations of active travel, organised sport and physical education with accelerometer-assess…

2022

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Additional file 7 of Cross-sectional and longitudinal associations of active travel, organised sport and physical education with accelerometer-assess…

2022

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Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium:an application of I…

2014

Mega- or meta-analytic studies (e.g. genome-wide association studies) are increasingly used in behavior genetics. An issue in such studies is that phenotypes are often measured by different instruments across study cohorts, requiring harmonization of measures so that more powerful fixed effect meta-analyses can be employed. Within the Genetics of Personality Consortium, we demonstrate for two clinically relevant personality traits, Neuroticism and Extraversion, how Item-Response Theory (IRT) can be applied to map item data from different inventories to the same underlying constructs. Personality item data were analyzed in >160,000 individuals from 23 cohorts across Europe, USA and Australia…

DIMENSIONSDISORDERS515 PsychologyeducationPersonality AssessmentGenome-wide association studiesExtraversion PsychologicalNEO-PI5-FACTOR MODELGeneticsHumansGenetics(clinical)Ecology Evolution Behavior and SystematicsOriginal ResearchNeuroticismMeasurementNeurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7]Models StatisticalOther Research Radboud Institute for Health Sciences [Radboudumc 0]GENOME-WIDE METAANALYSISTEMPERAMENTASSOCIATIONAnxiety Disorders3142 Public health care science environmental and occupational healthMeta-analysisPhenotypeMEASUREMENT INVARIANCECLONINGERSUrological cancers Radboud Institute for Health Sciences [Radboudumc 15]REPLICATIONDevelopmental PsychopathologyItem-Response TheoryConsortiumGenome-Wide Association StudyPersonality
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Additional file 1 of Cross-sectional and longitudinal associations of active travel, organised sport and physical education with accelerometer-assess…

2022

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Additional file 4 of Cross-sectional and longitudinal associations of active travel, organised sport and physical education with accelerometer-assess…

2022

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Additional file 3 of Cross-sectional and longitudinal associations of active travel, organised sport and physical education with accelerometer-assess…

2022

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Additional file 8 of Cross-sectional and longitudinal associations of active travel, organised sport and physical education with accelerometer-assess…

2022

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Additional file 9 of Cross-sectional and longitudinal associations of active travel, organised sport and physical education with accelerometer-assess…

2022

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Additional file 6 of Cross-sectional and longitudinal associations of active travel, organised sport and physical education with accelerometer-assess…

2022

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Influence of Guideline Operationalization on Youth Activity Prevalence in the International Children's Accelerometry Database

2022

Introduction: The United Kingdom and World Health Organization recently changed their youth physical activity (PA) guidelines from 60 minutes of moderate-vigorous PA (MVPA) every day, to an average of 60 minutes of MVPA per day, over a week. The changes are based on expert opinion due to insufficient evidence comparing health outcomes associated with different guideline definitions. Further, inconsistent guideline operationalization impairs understanding of physical inactivity prevalence. This study used the International Children’s Accelerometry Database to compare approaches to calculating PA compliance among youth and associations with health indicators. Methods: Cross-sectional accelero…

Adolescent/dk/atira/pure/core/keywords/exercise_nutrition_and_health_sciencesPhysical Therapy Sports Therapy and Rehabilitation610 Medicine & health10060 Epidemiology Biostatistics and Prevention Institute (EBPI)VDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850ICADCross-Sectional Studies2732 Orthopedics and Sports MedicineACCELEROMETERAccelerometryCOMPLIANCEPrevalenceVIGOROUS-INTENSITY PHYSICAL ACTIVITYHumansOrthopedics and Sports MedicinePHYSICAL ACTIVITYSPS Exercise Nutrition and Health SciencesSedentary Behavior3612 Physical Therapy Sports Therapy and RehabilitationChildExercise
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