0000000000441803

AUTHOR

S. Camilleri

showing 3 related works from this author

A simplified clinical risk score predicts the need for early endoscopy in non-variceal upper gastrointestinal bleeding

2014

Abstract Background Pre-endoscopic triage of patients who require an early upper endoscopy can improve management of patients with non-variceal upper gastrointestinal bleeding. Aims To validate a new simplified clinical score (T-score) to assess the need of an early upper endoscopy in non variceal bleeding patients. Secondary outcomes were re-bleeding rate, 30-day bleeding-related mortality. Methods In this prospective, multicentre study patients with bleeding who underwent upper endoscopy were enrolled. The accuracy for high risk endoscopic stigmata of the T-score was compared with that of the Glasgow Blatchford risk score. Results Overall, 602 patients underwent early upper endoscopy, and…

MaleVariceal bleedingClinical scoremedicine.medical_treatmentSeverity of Illness IndexEndoscopy GastrointestinalHEMORRHAGERecurrenceRisk FactorsProspective StudiesAged 80 and overOUTCOMESFramingham Risk Scoremedicine.diagnostic_testIncidenceUpper endoscopyGastroenterologyMiddle AgedTIMESurvival RateItalyFemaleGastrointestinal HemorrhageClinical risk factormedicine.medical_specialtyRisk AssessmentDiagnosis DifferentialClinical score Endoscopy High endoscopic stigmata Upper gastrointestinal bleeding; GLASGOW-BLATCHFORD HEMORRHAGE TIME OUTCOMESmedicineHumansUpper gastrointestinal bleedingAgedHepatologybusiness.industryReproducibility of Resultsnon variceal upper gastrointestinal bleedingEndoscopymedicine.diseaseTriageGLASGOW-BLATCHFORDEndoscopySurgerySettore MED/18 - Chirurgia GeneraleEarly DiagnosisHigh endoscopic stigmataROC CurveTherapeutic endoscopyUpper gastrointestinal bleedingTriagebusinessFollow-Up StudiesDigestive and Liver Disease
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Resistance to clarithromycin and genotypes in Helicobacter pylori strains isolated in Sicily

2015

The resistance of Helicobacter pylori strains to clarithromycin is increasing in several developed countries and their association with a genetic pattern circulation has been variously explained as related to different geographical areas. In this study we have reported: the prevalence of the resistance of H. pylori, isolated in Sicily, to clarithromycin; the principal point of mutation associated with this resistance; and the more frequent association between resistance to clarithromycin and cagA, the EPIYA motif, and the vacA and oipA genes. Resistance to clarithromycin was detected in 25 % of cases, the main genetic mutation involved being A2143G. The cagA gene was present in 48 % of case…

Microbiology (medical)Settore MED/07 - Microbiologia E Microbiologia ClinicaVirulence FactorsMolecular Sequence Datamedicine.disease_causeMicrobiologyMicrobiology (medical); MicrobiologyMicrobiologyHelicobacter InfectionsBacterial ProteinsClarithromycinClarithromycinGenotypeDrug Resistance BacterialmedicinePrevalenceCagAHumansAlleleGeneSicilyMutationbiologyHelicobacter pyloriPrincipal pointGeneral MedicineHelicobacter pyloribacterial infections and mycosesbiology.organism_classificationVirologyAnti-Bacterial Agentsmedicine.drug
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P288 Vedolizumab May Be An Effective Option For The Management Of Postoperative Recurrence Of Crohn’s Disease

2021

Abstract Background The role of Vedolizumab (VDZ) as therapeutic option for the postoperative recurrence of Crohn’s disease (CD) following ileocolonic resection is currently unknown. We aimed to assess the effectiveness of VDZ in this setting. Methods All consecutive CD patients with an available baseline colonoscopy at 6-12 months from the ileocolonic resection and treated with VDZ for the postoperative recurrence after the baseline colonoscopy were extracted from the cohort of the Sicilian Network for Inflammatory Bowel Diseases (SN-IBD). The primary outcome was endoscopic success, assessed at the first colonoscopy following initiation of VDZ. In patients with Rutgeerts score i0 or i1 at …

medicine.medical_specialtyCrohn's diseasemedicine.diagnostic_testbusiness.industryGastroenterologyColonoscopyGeneral Medicinemedicine.diseaseGastroenterologyInflammatory bowel diseaseEndoscopyVedolizumabInternal medicinemedicinebusinessmedicine.drugJournal of Crohn's and Colitis
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