0000000000442464
AUTHOR
Dumas F.
Telomeric sequences distribution in nine Neotropical primates (Platyrrhinae) by (TTAGGG)n probe mapping: interstitial location and their possible role in evolution
Platyrrhini are characterized by a high intra and intergeneric genome variability. This genome variability due to intra and inter-chromosomal rearrangements occurred during evolution could be possibly link to the involvement of telomeric and heterochromatin sequences. Telomeres, the terminal regions of chromosomes, constituted of particular repeated DNA sequences (TTAGGG)n and proteins, are called true telomeres and have their role in determining the replication and the stability of chromosomes. The DNA component of telomeres can be also found at intra-chromosomal sites such as close the centromeres and between centromere and telomeres, and are known as Interstitial Telomeric Sequences (ITS…
Chromosomal Localization of 18S-28S rDNA and (TTAGGG)n Sequences in Two South African Dormice of the Genus Graphiurus (Rodentia: Gliridae).
Classical cytogenetics and mapping of 18S-28S rDNA and (TTAGGG)<>n sequences by fluorescence in situ hybridization (FISH) was performed on Graphiurus platyops (GPL) and Graphiurus ocularis (GOC) metaphases with the aim to characterize the genomes. In both species, inverted DAPI karyotypes showed the same diploid number, 2n = 46, and hybridization of the (TTAGGG)<>n probe revealed interstitial telomeric sequences (ITSs) at the centromeres of almost all bi-armed chromosomes. FISH with the rDNA probe localized nucleolus organizer regions (NORs), at the terminal ends of the p arms of the telocentric pairs 16 and 17 in both species and detected additional signals on GPL8 and GOC18, 1…