International Society for Therapeutic Ultrasound Conference 2016

Supplemental_material - An International Survey of Quality and Safety Programs in Radiology

Supplemental_material for An International Survey of Quality and Safety Programs in Radiology by Jeremy Dick, Kathryn E. Darras, Frank J. Lexa, Erika Denton, Shigeru Ehara, Howard Galloway, Bhavin Jankharia, Pam Kassing, Kanako Kunishima Kumamaru, Peter Mildenberger, Sergey Morozov, Nadya Pyatigorskaya, Bin Song, Jacob Sosna, Marcus van Buchem and Bruce B. Forster in Canadian Association of Radiologists Journal

An International Survey of Quality and Safety Programs in Radiology

Purpose: The aim of this study was to determine the status of radiology quality improvement programs in a variety of selected nations worldwide. Methods: A survey was developed by select members of the International Economics Committee of the American College of Radiology on quality programs and was distributed to committee members. Members responded on behalf of their country. The 51-question survey asked about 12 different quality initiatives which were grouped into 4 themes: departments, users, equipment, and outcomes. Respondents reported whether a designated type of quality initiative was used in their country and answered subsequent questions further characterizing it. Results: The re…

Mutations in ARL2BP, Encoding ADP-Ribosylation-Factor-Like 2 Binding Protein, Cause Autosomal-Recessive Retinitis Pigmentosa

Retinitis pigmentosa (RP) is a genetically heterogeneous retinal degeneration characterized by photoreceptor death, which results in visual failure. Here, we used a combination of homozygosity mapping and exome sequencing to identify mutations in ARL2BP, which encodes an effector protein of the small GTPases ARL2 and ARL3, as causative for autosomal-recessive RP (RP66). In a family affected by RP and situs inversus, a homozygous, splice-acceptor mutation, c.101−1G>C, which alters pre-mRNA splicing of ARLBP2 in blood RNA, was identified. In another family, a homozygous c.134T>G (p.Met45Arg) mutation was identified. In the mouse retina, ARL2BP localized to the basal body and cilium-associated…