0000000000447235

AUTHOR

Kevin D. Moeller

showing 6 related works from this author

Electrochemical synthesis of benzoxazoles from anilides - a new approach to employ amidyl radical intermediates.

2017

A novel electrochemical method for the synthesis of benzoxazoles from readily available anilides is reported. Various functionalities are tolerated and good yields can be achieved. By employing common electrode materials and a simple constant current protocol, this method is an attractive new alternative to conventional pathways.

Electrode material010405 organic chemistryChemistryMetals and AlloysGeneral Chemistry010402 general chemistryElectrochemistry01 natural sciencesCombinatorial chemistryCatalysis0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsMaterials ChemistryCeramics and CompositesConstant currentOrganic chemistryChemical communications (Cambridge, England)
researchProduct

Insights into the Mechanism of Anodic N–N Bond Formation by Dehydrogenative Coupling

2017

The electrochemical synthesis of pyrazolidine-3,5-diones and benzoxazoles by N-N bond formation and C,O linkage, respectively, represents an easy access to medicinally relevant structures. Electrochemistry as a key technology ensures a safe and sustainable approach. We gained insights in the mechanism of these reactions by combining cyclovoltammetric and synthetic studies. The electron-transfer behavior of anilides and dianilides was studied and led to the following conclusion: The N-N bond formation involves a diradical as intermediate, whereas the benzoxazole formation is based on a cationic mechanism. Besides these studies, we developed a synthetic route to mixed dianilides as starting m…

010405 organic chemistryDiradicalChemistryCationic polymerizationGeneral ChemistryBond formationBenzoxazole010402 general chemistryElectrochemistry01 natural sciencesBiochemistryCombinatorial chemistryCatalysis0104 chemical sciencesAnodechemistry.chemical_compoundColloid and Surface ChemistryOrganic chemistryJournal of the American Chemical Society
researchProduct

CCDC 1561793: Experimental Crystal Structure Determination

2017

Related Article: Tile Gieshoff, Anton Kehl, Dieter Schollmeyer, Kevin D. Moeller, Siegfried R. Waldvogel|2017|J.Am.Chem.Soc.|139|12317|doi:10.1021/jacs.7b07488

6-chloro-2-(N-(4-chlorophenyl)-11-dimethyl)propanamide-13-benzoxazoleSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 1561794: Experimental Crystal Structure Determination

2017

Related Article: Tile Gieshoff, Anton Kehl, Dieter Schollmeyer, Kevin D. Moeller, Siegfried R. Waldvogel|2017|J.Am.Chem.Soc.|139|12317|doi:10.1021/jacs.7b07488

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters4-((3-((4-(((111333-hexafluoropropan-2-yl)oxy)methyl)phenyl)amino)-22-dimethyl-3-oxopropanoyl)amino)phenyl trifluoromethanesulfonateExperimental 3D Coordinates
researchProduct

CCDC 1561792: Experimental Crystal Structure Determination

2017

Related Article: Tile Gieshoff, Anton Kehl, Dieter Schollmeyer, Kevin D. Moeller, Siegfried R. Waldvogel|2017|J.Am.Chem.Soc.|139|12317|doi:10.1021/jacs.7b07488

Space GroupCrystallographyCrystal System12-bis(4-chlorophenyl)-44-dimethyltetrahydropyridazine-36-dioneCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 1530094: Experimental Crystal Structure Determination

2017

Related Article: Tile Gieshoff, Anton Kehl, Dieter Schollmeyer, Kevin D. Moeller, Siegfried R. Waldvogel|2017|Chem.Commun.|53|2974|doi:10.1039/C7CC00927E

Space GroupCrystallographyCrystal SystemCrystal Structure2-phenyl-13-benzoxazol-6-yl trifluoromethanesulfonateCell ParametersExperimental 3D Coordinates
researchProduct