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RESEARCH PRODUCT

Electrochemical synthesis of benzoxazoles from anilides - a new approach to employ amidyl radical intermediates.

Kevin D. MoellerDieter SchollmeyerAnton KehlTile GieshoffTile GieshoffSiegfried R. Waldvogel

subject

Electrode material010405 organic chemistryChemistryMetals and AlloysGeneral Chemistry010402 general chemistryElectrochemistry01 natural sciencesCombinatorial chemistryCatalysis0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsMaterials ChemistryCeramics and CompositesConstant currentOrganic chemistry

description

A novel electrochemical method for the synthesis of benzoxazoles from readily available anilides is reported. Various functionalities are tolerated and good yields can be achieved. By employing common electrode materials and a simple constant current protocol, this method is an attractive new alternative to conventional pathways.

10.1039/c7cc00927ehttps://pubmed.ncbi.nlm.nih.gov/28232997