0000000000448168

AUTHOR

Jakob Lüker

0000-0003-4667-2200

showing 3 related works from this author

Five-year follow-up after catheter ablation of persistent atrial fibrillation using the stepwise approach and prognostic factors for success.

2015

Background— In the meantime, catheter ablation is widely used for the treatment of persistent atrial fibrillation (AF). There is a paucity of data about long-term outcomes. This study evaluates (1) 5-year single and multiple procedure success and (2) prognostic factors for arrhythmia recurrences after catheter ablation of persistent AF using the stepwise approach aiming at AF termination. Methods and Results— A total of 549 patients with persistent AF underwent de novo catheter ablation using the stepwise approach (2007–2009). A total of 493 patients were included (Holter ECGs ≥every 6 months). Mean follow-up was 59±16 months with 2.1±1.1 procedures per patient. Single and multiple procedu…

AdultMaleReoperationmedicine.medical_specialtyTime Factorsmedicine.medical_treatmentCatheter ablationKaplan-Meier EstimateDisease-Free SurvivalYoung AdultSex FactorsHeart RatePredictive Value of TestsRecurrenceRisk FactorsPhysiology (medical)Internal medicineHeart rateAtrial FibrillationmedicineTachycardia SupraventricularHumans610 Medicine & healthAgedRetrospective StudiesAged 80 and overbusiness.industryAtrial fibrillationRetrospective cohort studyMiddle Agedmedicine.diseaseSurgeryTreatment OutcomeAtrial FlutterPredictive value of testsPersistent atrial fibrillationMultivariate AnalysisCardiologyCatheter AblationElectrocardiography AmbulatoryFemaleCardiology and Cardiovascular MedicinebusinessStepwise approachAnti-Arrhythmia AgentsAtrial flutterFollow-Up StudiesCirculation. Arrhythmia and electrophysiology
researchProduct

Impact of biatrial defragmentation in patients with paroxysmal atrial fibrillation: Results from a randomized prospective study

2014

Single procedure success rates of pulmonary vein isolation (PVI) in patients with paroxysmal atrial fibrillation (PAF) are still unsatisfactory. In patients with persistent atrial fibrillation (AF), ablation of complex fractionated atrial electrograms (CFAEs) after PVI results in improved outcomes.We aimed to investigate if PAF-patients with intraprocedurally sustained AF after PVI might benefit from additional CFAE ablation.A total of 1134 consecutive patients underwent a first catheter ablation procedure of PAF between June 2008 and December 2012. In most patients, AF was either not inducible or terminated during PVI. In 68 patients (6%), AF sustained after successful PVI. These patients …

Malemedicine.medical_specialtyTime Factorsmedicine.medical_treatmentElectric CountershockCatheter ablationCardioversionPulmonary veinHeart Conduction SystemHeart RatePhysiology (medical)Internal medicineAtrial FibrillationmedicineHumansSinus rhythmProspective StudiesTachycardia ParoxysmalProspective cohort studyAtrial tachycardiabusiness.industryAtrial fibrillationMiddle Agedmedicine.diseaseAblationTreatment OutcomePulmonary VeinsAnesthesiaCatheter AblationCardiologyFemalemedicine.symptomElectrophysiologic Techniques CardiacCardiology and Cardiovascular MedicinebusinessFollow-Up StudiesHeart Rhythm
researchProduct

5-Year Outcome of Pulmonary Vein Isolation by Loss of Pace Capture on the Ablation Line Versus Electrical Circumferential Pulmonary Vein Isolation

2017

This study sought to compare long-term arrhythmia-free survival between electrical circumferential pulmonary vein isolation (PVI) and PVI with the endpoint of unexcitability along the ablation line.PVI is the standard ablation strategy of paroxysmal atrial fibrillation, although arrhythmia recurrence in long-term follow-up (FU) is high. The endpoint of unexcitability along the ablation line results in decreased arrhythmia recurrence compared to electrical PVI in 1-year FU.Seventy-four consecutive patients (age 62.5 ± 10.6 years; 70.3% male) with de novo paroxysmal atrial fibrillation who were initially included in our randomized trial and underwent catheter ablation at our institution were …

Malemedicine.medical_specialtymedicine.medical_treatmentElectric Stimulation TherapyCatheter ablation030204 cardiovascular system & hematologyPulmonary veinlaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled trialRecurrencelawInternal medicineAtrial FibrillationClinical endpointHumansMedicine030212 general & internal medicineAtrial tachycardiaAgedbusiness.industryCardiac Pacing ArtificialAtrial fibrillationMiddle AgedAblationmedicine.diseaseSurgeryCatheterTreatment OutcomePulmonary VeinsCatheter AblationCardiologyFemalemedicine.symptombusinessFollow-Up StudiesJACC: Clinical Electrophysiology
researchProduct