0000000000448313

AUTHOR

Alexander Immel

showing 2 related works from this author

Early cave art and ancient DNA record the origin of European bison

2016

The two living species of bison (European and American) are among the few terrestrial megafauna to have survived the late Pleistocene extinctions. Despite the extensive bovid fossil record in Eurasia, the evolutionary history of the European bison (or wisent, Bison bonasus) before the Holocene (<11.7 thousand years ago (kya)) remains a mystery. We use complete ancient mitochondrial genomes and genome-wide nuclear DNA surveys to reveal that the wisent is the product of hybridization between the extinct steppe bison (Bison priscus) and ancestors of modern cattle (aurochs, Bos primigenius) before 120 kya, and contains up to 10% aurochs genomic ancestry. Although undetected within the fossil re…

0301 basic medicineGeneral Physics and AstronomymegafaunaBison priscusMegafaunahybridizationBison bonasusComputingMilieux_MISCELLANEOUSHolocenePhylogenyMultidisciplinarygeography.geographical_feature_categoryGenomebiologyBisonFossilsQAmerican Bisonfossil recordMitochondrialPleistoceneEuropeCavesvisual_artSequence Analysis[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and PrehistoryPleistoceneEvolutionLife on LandScienceBison Pleistocene fossil record mitochondrial genome hybridizationSocio-culturaleZoologySteppe bisonDNA MitochondrialArticleGeneral Biochemistry Genetics and Molecular BiologyAncientEvolution Molecular03 medical and health sciencesPaleontologyCaveGeneticsPleistocene extinctionsAnimalsDNA Ancientvisual_art.artworkCell NucleusgeographyHuman GenomeMolecularSequence Analysis DNAGeneral ChemistryDNAAurochsbiology.organism_classificationEurpoean BisonBos primigenius030104 developmental biologyAncient DNAmitochondrial genomeAmerican bisonGenome MitochondrialCommentaryCattlePaintings
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A 5,000-year-old hunter-gatherer already plagued by Yersinia pestis.

2021

Summary A 5,000-year-old Yersinia pestis genome (RV 2039) is reconstructed from a hunter-fisher-gatherer (5300–5050 cal BP) buried at Riņņukalns, Latvia. RV 2039 is the first in a series of ancient strains that evolved shortly after the split of Y. pestis from its antecessor Y. pseudotuberculosis ∼7,000 years ago. The genomic and phylogenetic characteristics of RV 2039 are consistent with the hypothesis that this very early Y. pestis form was most likely less transmissible and maybe even less virulent than later strains. Our data do not support the scenario of a prehistoric pneumonic plague pandemic, as suggested previously for the Neolithic decline. The geographical and temporal distributi…

0301 basic medicinePneumonic plagueaDNAQH301-705.5Yersinia pestisZoologyGeneral Biochemistry Genetics and Molecular Biologyhunter-gathererPrehistory03 medical and health sciences0302 clinical medicinemedicineHumansBiology (General)Hunter-gathererPhylogenyLikelihood FunctionsPlaguebiologyPhylogenetic treeZoonosiszoonosismedicine.diseasebiology.organism_classificationLatvia030104 developmental biologyYersinia pestis030217 neurology & neurosurgeryCell reports
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