Polyphenol intake and cardiovascular risk factors in a population with type 2 diabetes: The TOSCA.IT study

Background: The role of polyphenol intake on cardiovascular risk factors is little explored, particularly in people with diabetes. Aim: To evaluate the association between the intake of total polyphenols and polyphenol classes with the major cardiovascular risk factors in a population with type 2 diabetes. Methods: Dietary habits were investigated in 2573 males and females participants of the TOSCA.IT study. The European Prospective Investigation on Cancer and Nutrition (EPIC) questionnaire was used to assess dietary habits. In all participants, among others, we assessed anthropometry, plasma lipids, blood pressure, C-reactive protein and HbA1c following a standard protocol. The USDA and Ph…

Towards the identification and quantification of candidate metabolites of tebuconazole fungicide

International audience; Tebuconazole belongs to the family of triazole fungicides, used for crop protection and human health applications. In the environment, the dissipation of the parent molecule leads to the formation of metabolites that are of unknown identity or toxicity. In order to identify and determine the putative identity of those metabolites and their po- tential toxicity, a quadrupole time-of-flight (Q-TOF) approach is often used. Q-SAR approaches help to predict their toxicity by comparing them to a known database of molecules with known properties. All together the information on the candidate by-products may help to select relevant sub-set of metabolites for further quantifi…

Impact of a Pitanga Leaf Extract to Prevent Lipid Oxidation Processes during Shelf Life of Packaged Pork Burgers: An Untargeted Metabolomic Approach

In this work, the comprehensive metabolomic changes in pork burgers treated with different antioxidants, namely, (a) a control without antioxidants, (b) 200 mg/kg butylated hydroxytoluene (BHT), and (c) 250 mg/kg pitanga leaf extract (PLE, from Eugenia uniflora L.), each one packaged under modified atmosphere (80% O2 and 20% CO2) for 18 days storage at 2 &plusmn

Evidence for the interest of suspect screening metabolomics to identify known and unkown pesticide metabolites in soil

Assessment of nitrate contamination risk: The Italian experience

16 páginas, 19 figuras, 10 tablas.-- El PDF es el manuscrito aceptado para su publicación.-- et al.

Lab-to-field experimental approach to study the dissipation, metabolism, and soil microbial ecotoxicity of isoproturon, tebuconazole, and chlorpyrifos

International audience

New approach to identify and categorize pesticide metabolites in soil combining suspect screening metabolomics with in silico molecular typology. 5th International Conference on Environmental Pollution and Remediation (ICEPR)

New approach to identify and categorize pesticide metabolites in soil combining suspect screening metabolomics with in silico molecular typology. 5th International Conference on Environmental Pollution and Remediation (ICEPR). 5th International Conference on Environmental Pollution and Remediation (ICEPR)

Do we need a new regulatory framework for assessing the soil microbial ecotoxicity of pesticides?

International audience

Evaluation of the environmental fate and ecotoxicological impact of the pesticide chlorpyrifos in soil for improvement of its environmental risk assessment

EABIOMEUBINRA; Pesticides protect crops from various pests but can also harm nontarget organisms. To minimize risks for the environment and human health, a huge amount of studies are carried out and evaluated during the authorization process of each pesticide. However, the prediction of the environmental fate and ecotoxicological impact of a pesticide remains difficult. Several 100 formerly used pesticides are now banned because unexpected risks emerged decades after their authorization. Risk assessment documents of the organophosphate insecticide chlorpyrifos (CHL) particularly lack information about its degradation and potential transformation products in soil, and its impact on non-targe…

A tiered-based approach to study the dissipation and adsorption of isoproturon, tebuconazole and chlorpyrifos in soil

Fate and metabolism of the herbicide isoproturon in soil microcosms and its impact on soil microbial communities using advanced molecular tools

International audience

Pourquoi faut-il se préoccuper de la toxicité des pesticides pour les microorganismes du sol ?

EABIOmE INRA; Pourquoi faut-il se préoccuper de la toxicité des pesticides pour les microorganismes du sol ?

Risk-benefit in food safety and nutrition - outcome of the 2019 Parma Summer School

Risk-benefit assessment is the comparison of the risk of a situation to its related benefits, i.e. a comparison of scenarios estimating the overall health impact. The risk–benefit analysis paradigm mirrors the classical risk analysis one: risk–benefit assessment goes hand-in-hand with risk–benefit management and risk–benefit communication. The various health effects associated with food consumption, together with the increasing demand for advice on healthy and safe diets, have led to the development of different research disciplines in food safety and nutrition. In this sense, there is a clear need for a holistic approach, including and comparing all of the relevant health risks and benefit…

Untargeted screening of the bound / free phenolic composition in tomato cultivars for industrial transformation

BACKGROUND Tomato is one of the most important agricultural crops and it is characterized by a wide bioactive compound profile. However, little information is reported on its comprehensive polyphenol profile. In this work, 13 commercial tomato cultivars for industrial transformation were screened by ultra-high-pressure liquid chromatography coupled to quadrupole-time-of-flight mass spectrometry (UHPLC-QTOF-MS) for both free and bound phenolic profiles. Thereafter, the in vitro antioxidant activity of each cultivar was assessed by ferric reducing antioxidant power (FRAP) and oxygen radical absorbance activity (ORAC) assays. Multivariate statistics, i.e. orthogonal projection to latent struct…