0000000000452280

AUTHOR

G Savettieri

showing 8 related works from this author

Parkin gene analysis in late onset Parkinson's disease families

2004

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DJ-1 gene in late-onset recessive Parkinson's Disease

2004

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The Italian Multiple Sclerosis Database Network (MSDN): The risk of worsening according to IFNβ exposure in multiple sclerosis

2006

We evaluated the risk of worsening according to the length of exposure to interferon beta (IFNβ)ina large cohort of 2090 multiple sclerosis patients collected by the Italian MS Database Network. Overall 44-140 patient-visits with a follow-up of 22-143 patient-years were evaluated. Forty-one per cent of patients were exposed to IFNβ for up to 2 years, 39% for 2- 4 years and 20% for more than 4 years. A Cox regression model was used to analyse two clinical outcomes: disability progression and worsening of relapse rate. The technique of propensity score was applied to reduce bias in the comparison of non-randomized groups. The risks of disability progression (HR=0.23; 95% CI: 0.17 - 0.30) and …

AdultMaleTime Factorscomputer.software_genreCentral nervous system diseaseCohort Studies03 medical and health sciencesDisability Evaluation0302 clinical medicineAdjuvants ImmunologicmedicineHumansImmunologic Factors030212 general & internal medicineRisk factorMULTIPLE SCLEROSISDemographyProportional Hazards ModelsRISKAnalysis of VarianceDatabasebusiness.industryProportional hazards modelMultiple sclerosisInterferon-betaIFNP; Long term effectiveness; Multiple sclerosis; Observational studies;Middle Agedmedicine.diseaseTreatment OutcomeNeurologyDatabases as TopicItalyPropensity score matchingDisease ProgressionRegression AnalysisObservational studyFemaleNeurology (clinical)Analysis of variancebusinesscomputer030217 neurology & neurosurgeryCohort study
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Parkin gene analysis in late onset autosomal recessive Parkinson's Disease

2004

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Door-to-door prevalence survey of epilepsy in three Sicilian municipalities

2001

A door-to-door prevalence survey of epilepsy was conducted in 3 Sicilian municipalities, as of November 1, 1987. In phase 1, the screening by questionnaire of 24,496 eligible subjects (participation = 92%) identified 544 suspected to have epilepsy. In phase 2, neurological evaluation of the 544 subjects yielded 111 with epilepsy. Of the 111 subjects, 103 (93%) had been previously diagnosed, 68 (61%) were taking antiepileptic medication, and 81 (73%) had active epilepsy. Referring to the 81 subjects with active epilepsy, the seizure type was generalized in 60 (74%), partial in 19 (23%) and undetermined in 2 (3%). The prevalence of active epilepsy (per 1,000 population) was 3.3 overall, 3.5 f…

AdultMalePediatricsmedicine.medical_specialtyAdolescentEpidemiologyPopulationEpilepsySeizuresPrevalenceMedicineHumanseducationSurveyChildSicilyAgedAged 80 and overeducation.field_of_studyEpilepsybusiness.industryAge FactorsPrevalence surveyMiddle Agedmedicine.diseaseHealth Surveyslanguage.human_languageChild PreschoollanguageScreeningSettore MED/26 - NeurologiaFemaleNeurology (clinical)businessSicilian
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Computer-assisted cognitive remediation for Parkinson’s disease

2012

computer-assisted cognitive training parkinson's diseaseSettore MED/26 - Neurologia
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Accuracy of death certificates for amyotrophic lateral sclerosis varies significantly from north to south of Italy: Implications for mortality studies

2004

<i>Objective:</i> To evaluate the accuracy of death certificates (DCs) for amyotrophic lateral sclerosis (ALS) in different parts of Italy. Studies based on DC diagnosis for ALS have shown a reduced mortality comparing northern with southern Italy. These data are in contrast with results from other surveys on the incidence of ALS performed in Italy and other countries. <i>Methods:</i> Archives of neurological clinics from northern (Milano, Monza, Pavia, and Bologna) and southern Italy including islands (Napoli, Sassari, Palermo, and Messina) were searched for patients discharged with a diagnosis of ALS in the period 1970–1995. Subjects affected by definite/probable A…

AdultMaleGerontologyPediatricsmedicine.medical_specialtyEpidemiologyMEDLINEDeath CertificatesCause of DeathmedicineHumansMortalityAmyotrophic lateral sclerosisAgedCause of deathAged 80 and overAmyotrophic lateral sclerosis .business.industryIncidenceIncidence (epidemiology)Amyotrophic Lateral SclerosisReproducibility of ResultsMiddle Agedmedicine.diseaseDeath certificateItalyFemaleNeurology (clinical)business
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GREY MATTER ATROPHY AND FATIGUE IN MULTIPLE SCLEROSIS: A CORRELATION EVIDENT ONLY IN PATIENTS WITH LOW DISABILITY

2006

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