0000000000458379
AUTHOR
Germana
The user’s perspective in architectural heritage
Currently, the awareness has been widely acquired that appropriate use is an important condition for saving architectural heritage: as well as many others requisites (manageability, maintainability, and security) similarly accessibility has become common to any settlement, including the built heritage. Keeping in mind this general framework, the paper will outline the link between architec- tural heritage and the user’s perspective, intended as the paramount basis both of technological design and health science. The intertwined relationships between socio-cultural and economical aspects clarify the features of the use of this specific form of built environment, proposed as a thought provoki…
Valorization of apple peels through the study of the effects on the amyloid aggregation process of ?-casein
Waste valorization represents one of the main social challenges when promoting a circular economy and environmental sustainability. Here, we evaluated the effect of the polyphenols extracted from apple peels, normally disposed of as waste, on the amyloid aggregation process of ?-casein from bovine milk, a well-used amyloidogenic model system. The effect of the apple peel extract on protein aggregation was examined using a thioflavin T fluorescence assay, Congo red binding assay, circular dichroism, light scattering, and atomic force microscopy. We found that the phenolic extract from the peel of apples of the cultivar "Fuji", cultivated in Sicily (Caltavuturo, Italy), inhibited ?-casein fib…