0000000000459266
AUTHOR
C. Pasquale
showing 2 related works from this author
“Oxaliplatin plus high dose folinic acid and 5-fluoruracil i.v. bolus (OXAFAFU) versus irinotecan plus high dose folinic acid and 5-fluoruracil i.v. …
2005
PURPOSE: The primary end point of this phase III trial was to compare the response rate (RR) of oxaliplatin (OXA) plus levo-folinic acid (l-FA) and 5-fluorouracil (5-FU) bolus with that of irinotecan (IRI) plus l-FA and 5-FU bolus in advanced colorectal carcinoma. PATIENTS AND METHODS: Patients with measurable metastatic colorectal carcinoma were randomly allocated to receive: IRI 200 mg/m(2) on day 1, l-FA 250 mg/m(2) intravenously plus 5-FU 850 mg/m(2) on day 2 (IRIFAFU); or OXA 100 mg/m(2) on day 1, l-FA 250 mg/m(2) plus 5-FU 1050 mg/m(2) on day 2 [OXAFAFU high dose (hd)]. Cycles were given every 2 weeks. After a planned interim analysis, OXA was reduced to 85 mg/m(2) and 5-FU to 850 mg/…
Physicochemical characteristics and phenotypic diversity of sicilian winter pumpkin (Cucurbita maxima) populations
2017
Six pumpkin genotypes (G1, G2, G3, G4, G5 and G6) were evaluated for their morphological, agronomical and physico-chemical properties under ecological conditions of Sicily (Italy). Considering the agronomical, morphological and physicochemical data including fiber, humidity, pH, total acidity, soluble solids, carotenoids, phenolic and ascorbic acid content, it was possible to differentiate among genotypes. The morphological analysis showed that the pumpkin genotypes did not have a homogenous morphology and present a large physico-chemical characteristic variability. Furthermore, high contents of carotenoids and dietary fiber, soluble solids, phenolic and ascorbic acid were observed with the…