0000000000461955

AUTHOR

Amanda Caruselli

showing 9 related works from this author

Characteristics and care pathways of advanced cancer patients in a palliative-supportive care unit and an oncological ward.

2018

Abstract BACKGROUND: A supportive palliative care unit (SPCU) may have a positive impact on patients' care. The aim of this study was to compare the pattern of patients admitted to a specialized SPCU and to a traditional oncologic ward (OW) in a consecutive sample of advanced cancer patients. METHODS: Data on patients demographics, reasons for and kind of admission, care-giver, anticancer treatments, being on/off treatment or uncertain, origin setting, who proposed hospital admission, the use of opioids, and hospitalization were gathered. The same parameters were recorded at discharge. A follow-up was performed by phone 1 month after discharge. RESULTS: Two-hundred patients were surveyed. A…

Malemedicine.medical_specialtyPalliative caremedicine.medical_treatmentDiseaseMedical Oncology03 medical and health sciences0302 clinical medicineNeoplasmsmedicineHumans030212 general & internal medicineAgedChemotherapybusiness.industryPalliative CareAfter dischargeHospital admissionAdvanced cancer patientAdvanced cancerHospitalizationOncology030220 oncology & carcinogenesisUncontrolled painEmergencyEmergency medicineHospital admissionFemaleOff TreatmentbusinessSupportive careSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
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Patients' Acceptability of Different Fentanyl Products for Breakthrough Cancer Pain

2014

OTFC (6) 1.7 (0.5) 1.5 (0.5) 2.0 (0.6) 1.5 (0.8) 1.5 (0.5) 33.1 (43.5) FBT (19) 2.0 (0.6) 2.0 (0.7) 1.8 (0.7) 1.8 (0.8) 1.9 (0.7) 15.9 (7.3) SLF (37) 2.1 (0.5) 2.2 (0.4) 1.8 (0.4) 2.0 (0.6) 2.1 (0.5) 16.7 (12.5) INFS (7) 2.1 (0.4) 2.1 (0.4) 2.0 (0.6) 2.0 (0.8) 2.0 (0.8) 15.7 (13.7) PFEN (11) 2.4 (0.5) 2.2 (0.4) 1.8 (0.4) 1.9 (0.7) 2.1 (0.5) 15.0 (13.7) P 0.120 0.043* 0.870 0.595 0.178 0.015x *,x Oral transmucosal fentanyl was significantly considered to be more problematic.

Settore MED/06 - Oncologia Medicabusiness.industryBreakthrough PainBreakthrough PainPatient Acceptance of Health CareSettore MED/42 - Igiene Generale E ApplicatafentanylFentanylbreakthrough cancer painBTPOncologyNeoplasmsAnesthesiaAdministration MucosalHumansMedicineRadiology Nuclear Medicine and imagingpatient's preferencefentanyl; breakthrough cancer pain; BTP; patient's preferencebusinessCancer painmedicine.drugClinical Oncology
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Pain intensity as prognostic factor in cancer pain management

2015

Aim The aim of this study was to prospectively assess the prognostic value of initial pain intensity and its duration in advanced cancer patients. Methods A prospective study was conducted in a sample of patients with cancer requiring pain control. Patients underwent standard analgesic strategies used in our palliative care units. Pain intensity was measured at admission (T0) and after successful dose titration or opioid/route switching within a week (Ts). Patients were also asked about their pain intensity reported 15 days before admission (T-15). Doses of opioids and duration of opioid use were recorded. Patients were also assessed for the presence of incident pain, neuropathic pain, alco…

MalePalliative careSettore MED/42 - Igiene Generale E ApplicataSeverity of Illness IndexPain assessmentNeoplasms80 and overProspective StudiesCancer painProspective cohort studyCancerPain MeasurementAged 80 and overPrognostic factorAnalgesicsPalliative CareAssessment tools; Cancer; Cancer pain; Opioid; Opioid analgesics; Opioid response; Pain assessment; Pain intensity; Pain measurement; Prognostic factors; Aged; Aged 80 and over; Analgesics; Analgesics Opioid; Female; Humans; Logistic Models; Male; Middle Aged; Neoplasms; Neuralgia; Pain; Pain Management; Pain Measurement; Palliative Care; Prognosis; Prospective Studies; Stress Psychological; Treatment Outcome; Severity of Illness Index; Anesthesiology and Pain MedicineAssessment toolMiddle AgedPrognosisAnalgesics OpioidAssessment toolsTreatment OutcomeAnesthesiaNeuropathic painFemalemedicine.drugOpioid responsePain assessmentAnalgesicPainOpioidPain intensityPrognostic factorsStressOpioid analgesicAssessment tools; Cancer; Cancer pain; Opioid; Opioid analgesics; Opioid response; Pain assessment; Pain intensity; Pain measurement; Prognostic factors; Anesthesiology and Pain MedicinemedicineHumansPain ManagementAdverse effectAgedbusiness.industryAnesthesiology and Pain MedicineLogistic ModelsOpioidOpioid analgesicsPsychologicalNeuralgiaCancer painbusinessStress Psychological
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The use of ketamine in a palliative-supportive care unit: a retrospective analysis.

2018

Background: To assess the response to ketamine in patients with difficult pain syndromes. Methods: The charts of patients with uncontrolled pain despite opioid dose escalation of at least two opioids or a combination of them, selected for a burst of ketamine and midazolam were reviewed. One hundred mg/day of ketamine and midazolam 15 mg/day by a continuous intravenous infusion for about 48 hours was offered to patients. Results: Forty-four patients received a burst of ketamine. Ten patients did not achieve any improvement. Pain intensity decreased from a mean of 7.8 (SD, 1.6) to 2.8 (SD, 1.3) (P<0.0005). The outcome was considered optimal, good, and mild in 24, 9, and 1 patients, respective…

AdultMalePalliative careMidazolamAdverse effect03 medical and health sciences0302 clinical medicineRetrospective analysisMedicineHumansPain ManagementKetamine030212 general & internal medicineAdverse effectRefractory painAgedRetrospective StudiesAdvanced and Specialized NursingAged 80 and overbusiness.industryPalliative CareRetrospective cohort studyCancer PainMiddle AgedAnalgesics OpioidAnesthesiology and Pain MedicineOpioidChemotherapy AdjuvantAnesthesiaMidazolamFemaleKetaminebusinessCancer pain030217 neurology & neurosurgerymedicine.drugAnnals of palliative medicine
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Frequency and Indications of Parenteral Nutrition in an Acute Palliative Care Unit

2015

The aim of this study was to estimate the use of parenteral nutrition (PN) in advanced cancer patients enrolled in an acute pain relief and palliative care unit of a comprehensive cancer center and the appropriateness of the criteria to select patients for PN. Fourteen out of 750 patients (1.8%) admitted to an acute palliative care unit were administered PN. Patients were referred from various settings. The mean age was 58 yr (range 37-79), and 9 were males. The mean hospital stay was 7.7 days (range 3-14), and the mean Karnofsky level was 35 (range 10-50). The principal indication was bowel obstruction. Ten patients (71%) were already receiving PN before admission, and 2 of them discontinu…

AdultMaleCancer ResearchPediatricsmedicine.medical_specialtyParenteral NutritionPalliative careMedicine (miscellaneous)medicineHospital dischargeHumansProspective StudiesProspective cohort studyAgedNutrition and Dieteticsbusiness.industryPalliative CareMean ageLength of StayMiddle Agedmedicine.diseaseAdvanced cancerBowel obstructionProspective StudieParenteral nutritionTreatment OutcomeOncologyHospital admissionFemalebusinessHuman
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Sleep Disturbances in Patients with Advanced Cancer in Different Palliative Care Settings.

2015

Abstract Context Information regarding sleep disturbances in the population with advanced cancer is meager. Objectives To assess the prevalence of sleep disturbances and possible correlations with associated factors in a large number of patients with advanced cancer admitted to different palliative care settings. Methods This was an observational study performed in different settings of palliative care. A consecutive sample of patients with advanced cancer was prospectively assessed for a period of six months. Epidemiological and clinical data, treatments received in the last month, Karnofsky status, Edmonton Symptom Assessment System scores, and concomitant medical treatment were recorded.…

medicine.medical_specialtyPediatricsPalliative careCross-sectional studyinsomniaPopulationSleep disturbanceadvanced cancer; insomnia; palliative care; Sleep disturbances; Anesthesiology and Pain Medicine; Neurology (clinical); Nursing (all)2901 Nursing (miscellaneous)Sleep Wake DisordersHospital Anxiety and Depression ScalemedicineInsomniaadvanced cancerAthens insomnia scaleeducationProspective cohort studyGeneral NursingNursing (all)2901 Nursing (miscellaneous)education.field_of_studypalliative carebusiness.industrySleep disturbancesAnesthesiology and Pain MedicinePhysical therapyNeurology (clinical)medicine.symptombusiness
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The frequency of alcoholism in patients with advanced cancer admitted to an acute palliative care unit and a home care program

2015

Abstract Context Cancer patients with a history of alcoholism may be problematic. The frequency of alcoholism among patients with advanced cancer has never been reported in Italy or other European countries. Objectives The aim of this prospective study was to determine the frequency of alcoholism, assessed with a simple and validated instrument, among patients with advanced cancer who were referred to two different palliative care settings: an acute inpatient palliative care unit (PCU) of a comprehensive cancer center in a metropolitan area and a home care program (HCP) in a territorial district, localized in the mountains of Italy. Methods A consecutive sample of patients admitted to an in…

Malemedicine.medical_specialtyPediatricsPalliative careContext (language use)advanced cancer patientsNursingCancer Care Facilitiesadvanced cancer patients; Alcoholism; CAGE; palliative care; Anesthesiology and Pain Medicine; NursingSettore MED/42 - Igiene Generale E ApplicataInterviews as Topicadvanced cancer patientSex FactorsNeoplasmsSurveys and QuestionnairesmedicineHumansIn patientProspective StudiesKarnofsky Performance StatusPsychiatryProspective cohort studyGeneral NursingNursing (all)2901 Nursing (miscellaneous)Agedpalliative carePerformance statusbusiness.industryMedicine (all)Age FactorsCanceradvanced cancer patients; Alcoholism; CAGE; palliative care; Age Factors; Aged; Alcoholism; Female; Humans; Interviews as Topic; Italy; Karnofsky Performance Status; Male; Middle Aged; Neoplasms; Palliative Care; Prospective Studies; Sex Factors; Surveys and Questionnaires; Cancer Care Facilities; Home Care Services; Anesthesiology and Pain Medicine; Neurology (clinical); Nursing (all)2901 Nursing (miscellaneous); Medicine (all)Cancer Care FacilitiesMiddle Agedmedicine.diseaseHome Care ServicesAlcoholismAnesthesiology and Pain MedicineItalyCAGEFemaleNeurology (clinical)Care programbusiness
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The palliative-supportive care unit in a comprehensive cancer center as crossroad for patients' oncological pathway

2016

Aim The aim of this study was to assess how an admission to an acute palliative-supportive care unit (APSCU), may influence the therapeutic trajectory of advanced cancer patients. Methods A consecutive sample of advanced cancer patients admitted to APCU was assessed. The following parameters were collected: patients demographics, including age, gender, primary diagnosis, marital status, and educational level, performance status and reasons for and kind of admission, data about care-givers, recent anticancer treatments, being on/off treatment or uncertain, the previous care setting, who proposed the admission to APSCU. Physical and psychological symptoms were evaluated at admission and at ti…

MaleGenetics and Molecular Biology (all)Palliative careCancer Treatmentlcsh:MedicineMedicine (all); Biochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)ToxicologyPathology and Laboratory MedicineBiochemistryCONSECUTIVE SAMPLE0302 clinical medicineNeoplasmsMedicine and Health SciencesMedicine030212 general & internal medicinelcsh:ScienceAnalgesicsMultidisciplinaryPharmaceuticsMedicine (all)Palliative CareHormonal TherapyDrugsHospitalsPatient DischargeHospitalizationOncologyCritical Pathway030220 oncology & carcinogenesisCritical PathwaysMarital statusHormonal therapyFemaleOff TreatmentEnd-of-life careResearch ArticleHumanmedicine.medical_specialtyPatientsAged; Analgesics; Female; Follow-Up Studies; Hospitalization; Humans; Male; Neoplasms; Patient Discharge; Patient Readmission; Cancer Care Facilities; Critical Pathways; Palliative Care; Medicine (all); Biochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)Cancer Care FacilitiesPatient ReadmissionFollow-Up Studie03 medical and health sciencesDrug TherapyPain ManagementHumansIntensive care medicineAgedPharmacologyBiochemistry Genetics and Molecular Biology (all)ToxicityPerformance statusCancer Care Facilitiebusiness.industrylcsh:RBiology and Life SciencesCancermedicine.diseaseHealth CareOpioidsAgricultural and Biological Sciences (all)Health Care FacilitiesEmergency medicineNeoplasmlcsh:QAnalgesicbusinessFollow-Up Studies
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Epidemiology and Characteristics of Episodic Breathlessness in Advanced Cancer Patients. An Observational Study

2016

Abstract Context Episodic breathlessness is a relevant aspect in patients with advanced cancer. Objectives The aim of this study was to assess the different aspects of this clinical phenomenon. Methods A consecutive sample of patients with advanced cancer admitted to different settings for a period of six months was surveyed. The presence of background breathlessness and episodic breathlessness, their intensity (numerical scale 0–10), and drugs used for treatment were collected. Factors inducing episodic breathlessness and its influence on daily activities were investigated. Results Of 921 patients, 29.3% ( n  = 269) had breathlessness and 134 patients (49.8%) were receiving drugs for backg…

MalePediatricsmedicine.medical_specialtyPalliative careActivities of daily livingTime FactorsEpisodic breathlessneSettore MED/41 - AnestesiologiaContext (language use)advanced cancer; dyspnea; Episodic breathlessness; opioids; palliative care; Anesthesiology and Pain Medicine; Neurology (clinical); Nursing (all)2901 Nursing (miscellaneous)DiseaseComorbidityepisodic breathlessness; advanced cancer; dyspnea; opioids; palliative care03 medical and health sciencesPulmonary Disease Chronic Obstructive0302 clinical medicineNeoplasmsEpidemiologyActivities of Daily LivingmedicinePrevalenceHumansadvanced cancer030212 general & internal medicineKarnofsky Performance StatusGeneral NursingNursing (all)2901 Nursing (miscellaneous)Agedpalliative careEpisodic breathlessnessbusiness.industryEpisodic breathlessness; advanced cancer; dyspnea; opioids; palliative careopioidsCardiovascular Agentsrespiratory systemMiddle Ageddyspneamedicine.diseaseComorbidityAnesthesiology and Pain Medicine030220 oncology & carcinogenesisCardiovascular agentMultivariate AnalysisopioidObservational studyFemaleNeurology (clinical)business
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