0000000000461968

AUTHOR

Bruno Augusto Linhares Almeida Mariz

showing 2 related works from this author

CD1a+ and CD207+ cells are reduced in oral submucous fibrosis and oral squamous cell carcinoma

2019

Background The objective of this study investigated the distribution of immature dendritic cells (DCs), Langerhans cells and plasmacytoid DCs in oral submucous fibrosis (OSMF), OSMF associated with oral squamous cell carcinoma (OSMF-OSCC), oral leukoplakia (OL), and oral squamous cell carcinoma (OSCC). Material and Methods Fourteen cases of OSMF, 9 of OSMF-OSCC, 8 of OL¸ 45 of OSCC and 8 of normal epithelium were retrospectively retrieved and their diagnoses confirmed. Immunoreactions against CD1a, CD207 e CD303 were performed and the number of positive cells quantified. Results A significant decrease of CD1a+ was found in OSMF (p≤0.05), OSMF-OSCC (p ≤ 0.01), and OSCC (p ≤ 0.001) when compa…

medicine.medical_specialtyOral Submucous FibrosisGastroenterologyMalignant transformation03 medical and health sciences0302 clinical medicineImmune systemAntigenAntigens CDInternal medicinemedicineCarcinomaHumansLectins C-TypeGeneral DentistryLeukoplakiaRetrospective StudiesMouth neoplasmOral Medicine and Pathologybusiness.industryResearch030206 dentistry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseEpitheliumstomatognathic diseasesmedicine.anatomical_structureMannose-Binding LectinsOtorhinolaryngologyOral submucous fibrosisUNESCO::CIENCIAS MÉDICASCarcinoma Squamous CellSurgeryMouth NeoplasmsLeukoplakia OralbusinessMedicina Oral, Patología Oral y Cirugía Bucal
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Comparison of the whole slide imaging and conventional light microscopy in the grading of oral epithelial dysplasia: a multi-institutional study

2020

Made available in DSpace on 2021-06-25T11:48:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Background: Whole Slide Imaging (WSI) is an alternative method to light microscopy (LM). However, few studies have compared the diagnostic agreement between WSI and LM, especially to grade oral epithelial dysplasia (OED). The purpose of this study was to evaluate the variability in grading OED by the World Health Organization grading system, using WSI and conventional LM, and to investigate whether the access to clinical information, and psychologic or phy…

Epithelial dysplasiadiagnosisDigital analysisPositive correlationhead and neck neoplasmsMicroscopyHeart rateImage Interpretation Computer-AssistedphotobiomodulationPathologyMedicineHumansGrading (education)xerostomiaGeneral DentistryradiotherapyUNESCO:CIENCIAS MÉDICASAlternative methodsObserver Variationleukoplakia oralMicroscopysalivaHyperplasiaOral Medicine and Pathologybusiness.industryResearchanxietyOtorhinolaryngologymicroscopySurgerybusinessNuclear medicineKappaBrazil
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