0000000000462627

AUTHOR

A. Pala

showing 2 related works from this author

A 12-month prospective, observational study evaluating the impact of disease-modifying treatment on emotional burden in recently-diagnosed multiple s…

2016

Abstract Introduction Depression and anxiety are common among patients with multiple sclerosis (MS) and are frequently present at the time of MS diagnosis. Methods POSIDONIA was a 12-month, observational, prospective study conducted in Italy to evaluate the impact of disease-modifying treatment (DMT) on emotional burden in patients with recently-diagnosed MS. The Hospital Anxiety and Depression Scale (HADS), specifically HADS anxiety (HADS-A) and depression (HADS-D) subscale scores, the Short-Form 36 Health Survey (SF-36) and the Impact of Event Scale – Revised (IES-R) were used to measure patient-reported outcomes. The Hamilton Depression Rating Scale (HDRS), HDRS-17, was used as a measure…

MalePsychometricsAnxietyHospital Anxiety and Depression Scale0302 clinical medicineImmunologic FactorMultiple sclerosis Disease-modifying treatment Emotional burden Anxiety DepressionMultiple SclerosiDisease-modifying treatment030212 general & internal medicineProspective StudiesProspective cohort studyDepression (differential diagnoses)DepressionMiddle AgedPsychiatric Status Rating ScaleTreatment OutcomeItalyNeurologyAnxietyFemaleSettore MED/26 - Neurologiamedicine.symptomPsychologyPsychometricHumanAdultmedicine.medical_specialtyMultiple SclerosisMood DisorderPsychometricsAdolescentLogistic Model03 medical and health sciencesYoung AdultRating scalemedicineHumansImmunologic FactorsAgedPsychiatric Status Rating ScalesMood Disordersmedicine.diseaseProspective StudieLogistic ModelsMood disordersPhysical therapyEmotional burdenObservational studyNeurology (clinical)030217 neurology & neurosurgery
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Association of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes

2018

Background Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the development of stage ≥3 CKD has been less explored in type 1 diabetes mellitus (T1DM) patients. Aim of the present study was to evaluate the prognostic role of kidney disease measures, namely albuminuria and reduced GFR, on the development of stage ≥3 CKD in a large cohort of patients affected by T1DM. Methods A total of 4284 patients affected by T1DM followed-up at 76 diabetes centers participating to the Italian Association of Clinical Diabetologists (Associazione Medici D…

AdultMaleNephrologymedicine.medical_specialtyendocrine system diseasesRenal function030209 endocrinology & metabolism030204 cardiovascular system & hematologylcsh:RC870-923Kidneyurologic and male genital diseasesGFR03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicineDiabetes mellitusmedicineHumansAlbuminuriaDiabetic kidney diseaseKidneyType 1 diabetesurogenital systembusiness.industryIncidence (epidemiology)Middle Agedlcsh:Diseases of the genitourinary system. Urologymedicine.diseasefemale genital diseases and pregnancy complicationsAlbuminuria Diabetic kidney disease GFR NephrologyDiabetes Mellitus Type 1medicine.anatomical_structureItalyNephrologyDisease ProgressionAlbuminuriaFemalemedicine.symptombusinessResearch ArticleFollow-Up StudiesGlomerular Filtration RateKidney disease
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