0000000000462971

AUTHOR

Isabelle Huys

showing 4 related works from this author

Expert Opinion on Three Phage Therapy Related Topics: Bacterial Phage Resistance, Phage Training and Prophages in Bacterial Production Strain

2018

Phage therapy is increasingly put forward as a “new” potential tool in the fight against antibiotic resistant infections. During the “Centennial Celebration of Bacteriophage Research” conference in Tbilisi, Georgia on 26–29 June 2017, an international group of phage researchers committed to elaborate an expert opinion on three contentious phage therapy related issues that are hampering clinical progress in the field of phage therapy. This paper explores and discusses bacterial phage resistance, phage training and the presence of prophages in bacterial production strains while reviewing relevant research findings and experiences. Our purpose is to inform phage therapy stakeholders such as po…

resistancelääkeresistenssiprophagevirusesregulationadaptationtuotantobakteriofagitlääkesuunnittelufagiterapia
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Expert Opinion on Three Phage Therapy Related Topics: Bacterial Phage Resistance, Phage Training and Prophages in Bacterial Production Strains

2018

Phage therapy is increasingly put forward as a "new" potential tool in the fight against antibiotic resistant infections. During the "Centennial Celebration of Bacteriophage Research" conference in Tbilisi, Georgia on 26-29 June 2017, an international group of phage researchers committed to elaborate an expert opinion on three contentious phage therapy related issues that are hampering clinical progress in the field of phage therapy. This paper explores and discusses bacterial phage resistance, phage training and the presence of prophages in bacterial production strains while reviewing relevant research findings and experiences. Our purpose is to inform phage therapy stakeholders such as po…

0301 basic medicinephage therapyPhage therapyprophagemedicine.medical_treatmentviruses030106 microbiologylcsh:QR1-502Resistance (psychoanalysis)adaptationlcsh:MicrobiologyBacteriophageresistance03 medical and health sciencesAntibiotic resistanceVirologyPolitical sciencemedicineBacteriophageProphageComputingMilieux_MISCELLANEOUSbiologybusiness.industryConference ReportregulationPublic relationsResearch findingsbiology.organism_classification[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology3. Good healthInfectious DiseasesExpert opinionproductionbusinessViruses
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Patient Preferences for Lung Cancer Treatment: A Qualitative Study Protocol Among Advanced Lung Cancer Patients

2021

Introduction: Lung cancer is the deadliest and most prevalent cancer worldwide. Lung cancer treatments have different characteristics and are associated with a range of benefits and side effects for patients. Such differences may raise uncertainty among drug developers, regulators, payers, and clinicians regarding the value of these treatment effects to patients. The value of conducting patient preference studies (using qualitative and/or quantitative methods) for benefits and side effects of different treatment options has been recognized by healthcare stakeholders, such as drug developers, regulators, health technology assessment bodies, and clinicians. However, evidence-based guidelines …

medicine.medical_specialtyLung NeoplasmsDecision Making03 medical and health sciences0302 clinical medicineSDG 3 - Good Health and Well-beingCarcinoma Non-Small-Cell LungNominal group techniqueMethodsmedicineHumans030212 general & internal medicineLung cancerQualitative ResearchReimbursementpatient involvementbusiness.industrylcsh:Public aspects of medicinePublic Health Environmental and Occupational HealthHealth technologyCancerPatient Preferencelcsh:RA1-1270medicine.diseaseFocus groupdrug developmentlung cancerDrug developmentnominal group technique030220 oncology & carcinogenesisFamily medicinefocus group discussiondrug decision-makingPublic Healthbusinesspatient preferencesQualitative researchpatient-centered research
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Patient Preferences for Lung Cancer Treatments: A Study Protocol for a Preference Survey Using Discrete Choice Experiment and Swing Weighting

2021

Background: Advanced treatment options for non-small cell lung cancer (NSCLC) consist of immunotherapy, chemotherapy, or a combination of both. Decisions surrounding NSCLC can be considered as preference-sensitive because multiple treatments exist that vary in terms of mode of administration, treatment schedules, and benefit–risk profiles. As part of the IMI PREFER project, we developed a protocol for an online preference survey for NSCLC patients exploring differences in preferences according to patient characteristics (preference heterogeneity). Moreover, this study will evaluate and compare the use of two different preference elicitation methods, the discrete choice experiment (DCE) and …

medicine.medical_specialtyMedicine (General)Health literacyTask (project management)03 medical and health scienceseducational tool0302 clinical medicineQuality of life (healthcare)R5-920SDG 3 - Good Health and Well-beingMethodsmedicineMedical physicsPreference elicitationReimbursementnon-small cell lung cancerhealth locus of controlProtocol (science)030503 health policy & servicesdiscrete choice experimentGeneral MedicinePreferenceLocus of controlquality of life030220 oncology & carcinogenesisMedicineswing weighting0305 other medical sciencePsychologyhealth literacypatient preferenceFrontiers in medicine
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