0000000000463990

AUTHOR

Leporini Mariarosaria

showing 2 related works from this author

Investigating the Antiproliferative and Antioxidant Properties of

2018

Pancratium maritimum stems, flowers, bulbs, and fruits extracts were investigated for their antiproliferative and antioxidant properties. Total phenols and total flavonoids were also determined. The in vitro antiproliferative activity was tested against seven cancer cell lines such as C32, HeLa, MDA-MB-231, PC3, A549, MCF-7, and LNCaP by using SRB assay. Interesting results were obtained with stems ethanol extract (ET1) against C32 cells (IC50 of 27.1 μg/mL) and fruits aqueous extract (AQ) against MCF-7 cell line (IC50 of 36.5 μg/mL). To define the antioxidant activity, four tests such as DPPH, ABTS FRAP, and β-carotene bleaching tests were used. The most promising ABTS scavenging capacity …

Research ArticleEvidence-based complementary and alternative medicine : eCAM
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LC-ESI/HRMS analysis of glucosinolates, oxylipins and phenols in Italian rocket salad (Diplotaxis erucoides subsp. erucoides (L.) DC.) and evaluation…

2021

BACKGROUND: This study investigated the chemical profile and biological activity of Diplotaxis erucoides subsp. erucoides (L.) DC. (Brassicaceae) collected in Sicily (Italy). RESULTS: Liquid chromatography coupled with electrospray ionization and high-resolution mass spectrometry (LC-ESI/HRMS) analysis of the ethanol extract revealed the presence of 42 compounds – glucosinolates, hydroxycinnamic acids, flavonoids, and oxylipins. The extract was tested for its antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic) acid (ABTS), ferric reducing ability power (FRAP), and β-carotene bleaching tests. Promising protection from lipid peroxi…

Glucosinolatesantioxidant activityantioxidant activity; Diplotaxis erucoides; hypoglycemic and hypolipidemic effect; LC-ESI/HRMS analysis; Antioxidants; Brassicaceae; Chromatography Liquid; Enzyme Inhibitors; Flavonoids; Glucosinolates; Glycoside Hydrolase Inhibitors; Humans; Mass Spectrometry; Oxylipins; Plant Extracts; Salads; Sicily; alpha-Amylases; alpha-GlucosidasesAntioxidantsMass SpectrometrySettore BIO/01 - Botanica GeneraleLC-ESI/HRMS analysisHumansGlycoside Hydrolase InhibitorsOxylipinsEnzyme InhibitorsSicilyFlavonoidsChromatographyLiquidPlant ExtractsSettore BIO/02 - Botanica Sistematicaalpha-GlucosidasesSettore CHIM/06 - Chimica Organicahypoglycemic and hypolipidemic effectBrassicaceaeSettore BIO/03 - Botanica Ambientale E ApplicataDiplotaxis erucoidesSaladsalpha-AmylasesChromatography Liquid
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