0000000000464949

AUTHOR

Kai Lopau

showing 3 related works from this author

Rapid Steroid Withdrawal after Renal Transplantation Reduces Mortality: Five Year Follow-Up of a Randomized Controlled Trial (Harmony Study) Confirms…

2021

Background: We previously reported excellent efficacy and improved safety aspects of rapid steroid withdrawal (RSWD) in the randomized controlled one year “Harmony” trial, in which 587 predominantly deceased-donor kidney transplant recipients were randomized either to basiliximab or rabbit ATG induction therapy and compared to standard immunosuppressive therapy consisting of basiliximab, low tacrolimus once daily, mycophenolate mofetil, and corticosteroids. Methods: Following the end of the original one-year study period, patients were asked to participate in the observational follow-up (FU) study examining most of the end points of the original study. Hereby, de novo incidences between yea…

medicine.medical_specialtyeducation.field_of_studyBasiliximabbusiness.industryHazard ratioPopulationTacrolimuslaw.inventionTransplantationRandomized controlled triallawInternal medicinemedicineObservational studybusinesseducationSurvival ratemedicine.drugSSRN Electronic Journal
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High-urgency kidney transplantation in the Eurotransplant Kidney Allocation System : success or waste of organs? The Eurotransplant 15-year all-centr…

2016

Item does not contain fulltext BACKGROUND: In the Eurotransplant Kidney Allocation System (ETKAS), transplant candidates can be considered for high-urgency (HU) status in case of life-threatening inability to undergo renal replacement therapy. Data on the outcomes of HU transplantation are sparse and the benefit is controversial. METHODS: We systematically analysed data from 898 ET HU kidney transplant recipients from 61 transplant centres between 1996 and 2010 and investigated the 5-year patient and graft outcomes and differences between relevant subgroups. RESULTS: Kidney recipients with an HU status were younger (median 43 versus 55 years) and spent less time on the waiting list compared…

Graft RejectionMalemedicine.medical_treatmentMedizin030232 urology & nephrologygraft survival030230 surgery0302 clinical medicineSurveys and QuestionnairesDIALYSISYoung adultChildKidney transplantationCANDIDATESKidneyMiddle AgedPrognosis3. Good healthEuropeMulticenter Studymedicine.anatomical_structureNephrologyChild PreschoolFemaleHemodialysisAdultReoperationmedicine.medical_specialtykidneyTissue and Organ ProcurementAdolescentWaiting ListsDonor SelectionResource AllocationYoung Adult03 medical and health sciencespatient survivalInternal medicinemedicineJournal ArticleHumansComparative StudyRenal replacement therapyDialysisAgedbusiness.industryDonor selectionInfant NewbornInfantmedicine.diseaseKidney TransplantationSurgeryTransplantationhigh-urgencyPRIORITYSURVIVAL BENEFITrenalHuman medicineRenal disorders Radboud Institute for Health Sciences [Radboudumc 11]businessWAITING TIMEtransplantationNephrology, dialysis, transplantation
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Repeated kidney re-transplantation—the Eurotransplant experience: a retrospective multicenter outcome analysis

2020

Transplant international (2020). doi:10.1111/tri.13569

re-transplantationOutcome analysis030230 surgeryKidneyALLOCATION0302 clinical medicine3RDfourthKidney transplantationKidneychildGraft SurvivalConfoundinglossSUCCESSrepeatedGRAFT LOSSCOMPETING RISKSTissue Donorsddc:Treatment Outcomesurgical procedures operativemedicine.anatomical_structure030211 gastroenterology & hepatologyOutcome dataLife Sciences & Biomedicinemedicine.medical_specialtykidneyTissue and Organ ProcurementRe transplantation610survival1ST03 medical and health sciencesmedicineHumansddc:6102NDRetrospective StudiesDeceased donorTransplantationScience & Technologybusiness.industrymedicine.diseaseKidney TransplantationSurgeryTransplantationRECIPIENTSgraftSurgeryHuman medicinebusinessthirdSINGLE-CENTER
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