0000000000465368

AUTHOR

Krishna R. Veeramah

showing 6 related works from this author

Genomic Data from an Ancient European Battlefield Indicates On-Going Strong Selection on a Genomic Region Associated with Lactase Persistence Over th…

2020

Lactase persistence (LP), the continued expression of lactase into adulthood, is the most strongly selected single gene trait over the last 10,000 years in multiple human populations. It has been posited that the primary allele causing LP among Eurasians, rs4988235*T (Enattah et al. 2008), only rose to appreciable frequencies during the Bronze and Iron Ages (Mathieson et al 2015; Olalde et al. 2018), long after humans started consuming milk from domesticated animals. This rapid rise has been attributed to an influx of peoples from the Pontic-Caspian steppe that began around 5,000 years ago (Allentoft et al. 2015; Furholt et al. 2016). We investigate the spatiotemporal spread of LP through a…

geography050208 financegeography.geographical_feature_categorySteppemedicine.medical_treatment05 social sciencesZoologyPopulation geneticsLactaseengineering.materialLactase persistenceBronze AgeIron Age0502 economics and businessengineeringmedicine050207 economicsBronzeDomesticationSSRN Electronic Journal
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Early farmers from across Europe directly descended from Neolithic Aegeans

2015

WOS: 000378272400038

0301 basic medicineMediterranean climatePopulation03 medical and health sciences0302 clinical medicineGenetic similarityddc:590Humans0601 history and archaeologyAnatoliaNeolithiceducationQH426HoloceneMesolithic030304 developmental biology2. Zero hungerPrincipal Component Analysis0303 health scienceseducation.field_of_studyMultidisciplinary060102 archaeologyGreeceMediterranean RegionEcologybusiness.industrySedentismAgriculture06 humanities and the artsBiological SciencesCCCBEuropepaleogenomicsGenetics Population030104 developmental biologyGeographyAncient DNAPaleogenomicsAgricultureAnthropologyBiological dispersalbusiness030217 neurology & neurosurgeryMesolithic
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Ancient European dog genomes reveal continuity since the Early Neolithic

2017

Europe has played a major role in dog evolution, harbouring the oldest uncontested Palaeolithic remains and having been the centre of modern dog breed creation. Here we sequence the genomes of an Early and End Neolithic dog from Germany, including a sample associated with an early European farming community. Both dogs demonstrate continuity with each other and predominantly share ancestry with modern European dogs, contradicting a previously suggested Late Neolithic population replacement. We find no genetic evidence to support the recent hypothesis proposing dual origins of dog domestication. By calibrating the mutation rate using our oldest dog, we narrow the timing of dog domestication t…

0301 basic medicineMitochondrial DNAGenome evolution[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and PrehistoryScienceGeneral Physics and AstronomyPopulation geneticsPopulation ReplacementBiologyDNA MitochondrialGenomeArticleGeneral Biochemistry Genetics and Molecular BiologyDomesticationPaleontology03 medical and health sciencesDogs0302 clinical medicineAnimalsDomesticationComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesGenomeMultidisciplinaryQGenetic VariationGeneral Chemistry[SHS.ANTHRO-SE]Humanities and Social Sciences/Social Anthropology and ethnologyBiological EvolutionEastern europeanPhylogeography030104 developmental biologyGeographyEvolutionary biology[SHS.ENVIR]Humanities and Social Sciences/Environmental studiesPeriod (geology)Adaptation030217 neurology & neurosurgeryNature Communications
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Population genomic analysis of elongated skulls reveals extensive female-biased immigration in Early Medieval Bavaria

2018

Significance Many modern European states trace their roots back to a period known as the Migration Period that spans from Late Antiquity to the early Middle Ages. We have conducted the first population-level analysis of people from this era, generating genomic data from 41 graves from archaeological sites in present-day Bavaria in southern Germany mostly dating to around 500 AD. While they are predominantly of northern/central European ancestry, we also find significant evidence for a nonlocal genetic provenance that is highly enriched among resident Early Medieval women, demonstrating artificial skull deformation. We infer that the most likely origin of the majority of these women was sout…

0301 basic medicineHuman MigrationGenetic genealogyPopulationPopulation geneticsMigration PeriodGenetic analysisWhite PeoplePrehistory03 medical and health sciences0302 clinical medicineGermanyHumansEarly MedievalEast AsiaDNA Ancienteducationeducation.field_of_studyMultidisciplinaryPopulation BiologyWhole Genome SequencingGenome HumanGenetic heterogeneitySkullpopulation geneticsGenetic VariationGenomicsBiological Sciencesdemographic inferenceHistory MedievalpaleogenomicsGenetics PopulationPhenotype030104 developmental biologyGeographyArchaeologyHaplotypesEvolutionary biologyGenetic structureFemale030217 neurology & neurosurgeryProceedings of the National Academy of Sciences
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Low Prevalence of Lactase Persistence in Bronze Age Europe Indicates Ongoing Strong Selection over the Last 3,000 Years

2020

Lactase persistence (LP), the continued expression of lactase into adulthood, is the most strongly selected single gene trait over the last 10,000 years inmultiple human populations. It has been posited that the primary allele causing LP among Eurasians, rs4988235-A [1], only rose to appreciable frequencies during the Bronze and Iron Ages [2, 3], long after humans started consuming milk from domesticated animals. This rapid rise has been attributed to an influx of people from the Pontic-Caspian steppe that began around 5,000 years ago [4, 5]. We investigate the spatiotemporal spread of LP through an analysis of 14 warriors from the Tollense Bronze Age battlefield in northern Germany ( 3,20…

AdultMale0301 basic medicineSteppemedicine.medical_treatmentBiologyengineering.materialDNA MitochondrialWhite PeopleGeneral Biochemistry Genetics and Molecular BiologyYoung Adult03 medical and health sciences0302 clinical medicineGene FrequencyBronze AgeLactase persistenceHuman population geneticsmedicineHumansDNA AncientSelection GeneticBronzeDomesticationancient DNALactasegeographygeography.geographical_feature_categoryLactaseBody RemainsEuropeLactase persistence030104 developmental biologyIron AgeengineeringFemaleGeneral Agricultural and Biological Sciences030217 neurology & neurosurgeryDemography
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Kinship, acquired and inherited status, and population structure at the Early Bronze Age Mokrin necropolis in northern Serbia

2020

AbstractTwenty-four ancient genomes with an average sequencing coverage of 0.85±0.25 X were produced from the Mokrin necropolis, an Early Bronze Age (2,100-1,800 BC) Maros culture site in Serbia, to provide unambiguous identification of biological sex, population structure, and genetic kinship between individuals. Of the 24 investigated individuals, 15 were involved in kinship relationships of varying degrees, including 3 parent-offspring relationships. All observed parent-offspring pairs were mother and son. In addition to the absence of biological daughters, we observed a number of young women and girls with no biological relatives in our sample. These observations, together with the high…

0303 health scienceseducation.field_of_studyGrave goods060102 archaeologymedia_common.quotation_subjectExogamyPopulation06 humanities and the artsBiological MotherSocial stratification03 medical and health sciencesGeographyBronze AgeKinship0601 history and archaeologyeducation030304 developmental biologyDiversity (politics)media_commonDemography
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