0000000000465724

AUTHOR

Stephanie Berg

showing 2 related works from this author

Auditory cortex reflects goal-directed movement but is not necessary for behavioral adaptation in sound-cued reward tracking

2020

Mounting evidence suggests that the role of sensory cortices in perceptual decision making goes beyond the mere representation of the discriminative stimuli and additionally involves the representation of nonsensory variables such as reward expectation. However, the relevance of these representations for behavior is not clear. To address this issue, we trained rats to discriminate sounds in a single-interval forced-choice task and then confronted the animals with unsignaled blockwise changes of reward probabilities. We found that unequal reward probabilities for the two choice options led to substantial shifts in response bias without concomitant reduction in stimulus discrimination. Althou…

MalePhysiologyMovementPrefrontal CortexSensory systemStimulus (physiology)Auditory cortexChoice BehaviorDiscrimination PsychologicalRewardAdaptation PsychologicalmedicineAnimalsRats Long-EvansSensory cortexPrefrontal cortexAuditory CortexAdaptive behaviorGeneral NeuroscienceResponse biasAnticipationRatsmedicine.anatomical_structureAuditory PerceptionCuesPsychologyGoalsNeuroscienceJournal of Neurophysiology
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Olfaction in chemotherapy for head and neck malignancies

2015

Abstract Objective Systemic chemotherapy for different malignancies occurs alongside various side effects, including reduced sensory function. To date, little is known about the effect of chemotherapeutic agents on olfaction. The aim of this study was to provide new data about changes in sense of smell during chemotherapy among patients with advanced squamous cell carcinomas of the head and neck region. Methods In a prospective, controlled cohort study of patients undergoing up to three courses of chemotherapy (cis- or carboplatin, 5-fluorouracil and docetaxel), olfaction was evaluated prior to and directly following completing a cycle, as well as 3 weeks later with the beginning of the nex…

MaleOncologymedicine.medical_treatmentDocetaxelSystemic therapyCarboplatinCohort StudiesOlfaction Disorderschemistry.chemical_compound0302 clinical medicineAntineoplastic Combined Chemotherapy ProtocolsProspective Studies030212 general & internal medicineAged 80 and overSmokingAge FactorsGeneral MedicineMiddle AgedDocetaxelHead and Neck NeoplasmsSensory Thresholds030220 oncology & carcinogenesisCarcinoma Squamous CellFemaleTaxoidsFluorouracilmedicine.drugCohort studyAdultmedicine.medical_specialtyDifferential ThresholdOlfaction03 medical and health sciencesInternal medicinemedicineHumansLaryngeal NeoplasmsAgedCisplatinChemotherapySquamous Cell Carcinoma of Head and Neckbusiness.industryCancerPharyngeal Neoplasmsmedicine.diseaseCarboplatinSurgeryOtorhinolaryngologychemistryControlled Before-After StudiesSurgeryCisplatinbusinessAuris Nasus Larynx
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