0000000000470724

AUTHOR

Francisco Tomás Bosch

Tratamiento conservador del adenocarcinoma de endometrio. Obtención de dos gestaciones con recién nacidos sanos

Resumen Se presenta un caso de adenocarcinoma de endometrio bien diferenciado en una mujer de 30 anos, sin hijos, cuya lesion se trato con gestagenos y reseccion histeroscopica. Tras el tratamiento se consiguio una gestacion normal, que se siguio, durante 18 meses, de una anticoncepcion con un dispositivo intrauterino (DIU) de levonorgestrel. Tras retirar el DIU se consiguio otra gestacion normal. Finalmente, completados los deseos reproductivos, se practico una histerectomia total con doble anexectomia. Se comentan los aspectos eticos, diagnosticos y terapeuticos, asi como las incertidumbres que tuvimos que afrontar, incluida la posibilidad de progresion de las lesiones y defuncion de la p…

research product

Sex differences in estimation of time intervals and in reaction time are removed by moderate but not high doses of caffeine in coffee

Estimation of the passage of time in the seconds-to-minutes range and reaction time are strongly dependent on a hypothetical internal clock. Dopamine is the neurotransmitter most closely related to the rate of this clock. Caffeine, probably the most consumed drug in the world, leads to an augmentation of dopamine neurotransmission. In this study coffee, which reproduces the conditions under which caffeine is normally ingested, containing 3, 75, 150 or 300 mg of caffeine, was given to healthy male and female volunteers. A computerized time estimation and reaction time test was carried out 50 min after ingestion. Sex differences in placebo control subjects (who took decaffeinated coffee with …

research product

Capillary column gas chromatographic identification of sugars in honey as trimethylsilyl derivatives.

A method for identifying carbohydrates (mono-, di- and trisaccharides) in honey is presented. It is based on the separate preparation of both trimethylsilyl ethers and oxime trimethylsilyl ethers of the sugars followed by their gas chromatographic separation on a fused-silica capillary column coated with OV-101 using temperature programming. From the two chromatograms, the number of peaks given by each derivatized sugar, their relative retention times and peak-area ratios are used for identification. The identities of two unidentified trisaccharide peaks are considered. Quantitative applications to honey sugar analysis are discussed.

research product